Tuesday, August 19, 2014

Auto-Immune Antiphospholipid Cause and Other GMO Illnesses

Round-Up resistant crops are made by inserting a portion of DNA into the food, and that DNA comes from a type of bacteria that is resistant to Round-Up. While this genetic modification is successful in its primary goal of making food that is resistant to Round-Up, we do have a big problem if the mechanism of resistance involves an expression of any of the negatively charged proteins or lipids from the bacteria, on the outside of the plant cell.

For more than a year I did extensive study on the antimicrobial peptide mimic, CSA-13; it is a synthetic biomimetic compound that is active in the body much like ll-37.

CSA-13 has a strongly cationic (positively charged) head-group and a hydrophobic tail, but to make a long-story short: it is electrically attracted to the anionic (negatively charged) expression of pathogen membranes, whether that is the LTA, LPS, or the lipid bilayer of the membrane itself.

Once CSA-13 is attached, the hydrophobic tail inserts itself into the cell causing blebbing, apoptosis and cell death. MRSA, drug-resistant pseudomonas, and even multiple myeloma cells are utterly destroyed by this compound. It was my responsibility to understand, research, and characterize the membrane depolarization mechanisms of the compound.

Those negatively charged outer portions of the pathogens are what trigger the human immune response. The immune system is necessary in that can help us 'get better,' but it is not exactly 'healthy' to have this immune response triggered.

When the immune response is triggered, it is stressful to nearly every organ of the body. If the resistance to Round-Up is as previously described, then there is the possibility that these specific GM foods are subtle triggers of the human immune system; causing inflammation and potentially worse,unforeseen consequences...
(0:28) This article is 100% biased in favor of Monsanto's GMOs. So please, allow me a rapid fire counter-point:

(0:36) There may be no short-term negative health effects of GMOs, and if they'd been brought before the FDA anytime other than the deregulate-happy early 90's they'd have had to prove a bit more.

(0:45) There is one bacteria that's resistant to Round-Up, so they put its gene in our food. The problem is that the anionic outer membrane lipids are the gatekeepers, likely what we modified with bacterial DNA.

(0:56) And bacterial teichoic acids, and lipopolysaccharides, are what signal the human immune response and make us present 'sick symptoms' as we fight the bacteria. So now we get multiple daily doses of immune stress ingredients, which stresses out our whole body over our entire lives.

(1:12) Worst of all, these anionic immune stimulators are hidden in the zwitterionic membrane environment of our food; leaving the total membrane net neutral and effectively invisible to our cationic peptides and everything else that would fix the problem.

For those in the field, what happens when ll-37 is over-expressed in the bloodstream? What happens when they can't find a pathogen? Do they not lyse erythrocytes? Do they not destroy red blood cells? I know this because CSA-13 can do the same thing, although not nearly as much as ll-37, which makes it a good compound for study against pathogens.

I'll assume the professionals have made the mental leap already, so, let me spell it out for everyone else: not only are Round-Up resistant crops potential stressors for the body in small amounts, bit by bit over time, but when they trigger the immune response, it causes our peptides to go on the offensive; looking to kill.

The problem is that food cells express zwitterionic membranes (positive-negative-positive-negative) and as a whole, appear electrically neutral. This means that our peptides won't be able to find them, they won't have any 'bad' cells to attack, so, what is left? Red blood cells.

From there, you get into cytotoxic elements of the cell interiors that are perfectly fine inside the cell, but bad news if allowed to float freely in the bloodstream.

Round-Up resistant crops passed regulation on what is basically a "substantial equivalent" basis from the FDA. This was during Reagan's deregulation push, and the process is laughably less rigorous than EVERY standard through which drugs and devices are now forced to pass.

This is an unacceptable risk given the subject matter: food. It is also a legitimate concern given basic microbiology. This letter does not definitively prove anything, but it is imperative that further studies are conducted.

This author recommends a gene array analyses to ascertain all the subtle effects of the resistant expression of those foods, there are number of laboratories that can easily perform one; it may be as simple as that.

- Ben Davidson, JD


Where can you learn more about the information discussed in this article?

'Alberts Molecular Biology of the Cell.' 4th Ed. ©2002 New York, Garland Science.

Boman HG. 'Antibacterial Peptides: Basic facts and emerging concepts.' J Intern Med 2003; 254: 197-215.

Garimella et al. 'Conformation of the phosphate D-alanine zwitterion in bacterial teichoic acid from nuclear magnetic resonance spectroscopy.' Biochemistry, October 2009.

Glukhov et al. 'Basis for Selectivity of Cationic Antimicrobial Peptides for Bacterial Versus Mammalian Membranes.' J Biol Chem, October 2005.

Kim J. (July 1991) 'Binding of peptides with basic residues to membranes containing acidic phospholipids.' Biophys J. 60 (1): 135-48.

Matsuzaki et al. 'Molecular Basis for Membrane Selectivity of an Antimicrobial Peptide, magainin 2.' Biochemistry, March 1995.

Nan et al. 'Prokaryotic selectivity and LPS-netralizing activity of short antimicrobial peptides designed from the human antimicrobial peptide LL-37.' Peptides. June 2012.

Vance, DE. 'Biochemistry of Lipids, Lipoproteins and Membranes.' Elsevier. pp. 80-81. ISBN 0-444-89321-0.

Yeagle, P. 'The Membranes of Cells.' 2nd Ed. ©1993 Boston: Academic Press.

Fractals. It means that basic patterns repeat all throughout nature. It can be seen in branching veins in the human body, tributaries and streams of a river, and in this case, trees and human placentas. Essentially, the idea is that things will tend to branch out into new things as they continue on with natural processes.

Fractal nature...This is why messing with the tree of life is so wrong...DNA and RNA manipulation is the tree in the Bible and, a warning from the past...
The message just got mixed up...

Tuesday, August 12, 2014

GMO YEAST OMG! And Also Made Into "ORGANIC" Fertilizer? Now We Know In EVERYTHING!!!

Non-Food Commercial Uses of GM Baker's Yeast

Genetically modified Baker's yeast, also known by its scientific name Saccharomyces cerevisiae, is used in numerous commercial applications (and this New York Times article suggests that many new developments in the flavor and fragrance arena are underway). Drug companies use GM Baker's yeast to make the peptide hormone insulin and other drugs.
For decades, human insulin for diabetic medication has been produced in genetically modified Baker's yeast by Novo Nordisk, a GMO pharmaceutical company which is a sister company to Novozymes, a producer of genetically engineered food enzymes.

Accidental Environmental Release

Despite efforts to avoid environmental release of GMO yeast, Novo Nordisk has reported accidental spills over the years. Further, air emissions from the fermentation and recovery plants also contain GMOs, according to the company.
"The discharge to the air is below the limit value of 100,000 GMOs/m3 air as specified in the gene technology approvals... GMOs are also discharged into the waste water. The discharge is below the limit value of 10,000 GMOs/ml waste water as specified in the gene technology approvals." 
What happens if/when these GE yeast enter the environment? Novo Nordisk, which performs its own environmental disaster management and assessment, says its experience is that there is nothing to worry about:
"Very few accidental releases have actually occurred. We conduct investigations for GMOs in the environment around the factories on a regular basis, and we have never found any GMOs. Based on many years of experience it is our assessment that our genetically modified cells do not survive in nature. The cells are very weak and not fit to survive in the environment with scarce nutrients and competition from naturally occurring microorganisms." - Molecular microbiologist Niels Bagge, PhD employed by Novo Nordisk
It gives new meaning to Novozymes's tagline: Rethink Tomorrow.

Oversight and Regulation

Of course, since there is no third party verification, one cannot be certain if these GE yeast cells and their spores have not become established in the environment or the food chain.
Why are drug companies using Baker's yeast for GE pharmaceutical product manufacturing?
It's because the genetics of Baker's yeast have been worked out by geneticists, and its genome is easy to manipulate, adding new genes with ease. Just ferment the yeast, and it synthesizes whatever you designed it to produce.
More specifically then, why are corporations permitted to use Baker's yeast for non-food commercial purposes when it is precisely the same yeast used in our food supply?
It's because no one said they couldn't.

GE Yeast in Human Intestines for Medical Science?

What could happen if the GE Baker's yeast that produces insulin gets into the intestines of humans and starts producing insulin in the gut?
It could cause hyperinsulinemia, as excessive amounts of insulin are absorbed. The symptoms of hyperinsulinemia, by the way, include obesity and type 2 diabetes, as the excessive insulin causes cells to produce fat and absorb water.
Could this be a cause of the worldwide epidemic of obesity and type 2 diabetes? How much genetically modified yeast is needed in the intestines to cause a problem? The research into these questions is not being done.
When Novo Nordisk is finished using its yeast to ferment human insulin, the yeast is heat inactivated and fed to pigs. It is not mentioned in their procedure whether they test for yeast spores, which are heat stable. The pigs are noted to get fat on the slurry, which would happen with hyperinsulinemia.



Is Genetically Modified Baker's Yeast Spreading Obesity and Diabetes?
The fact that GE yeast can enter the intestines and produce physiological effects is being exploited by medical science. GE yeast is already under study as a way to deliver drugs and vaccines when taken orally. The yeast gets through the stomach and into the intestines where it can impact the body by releasing the products it was modified to produce. See, for example:
The current concern about inflammatory consequences of gluten-containing food consumption may actually be related to GE yeast contamination of these foods. Gluten exposure in sensitive individuals causes brain fatigue, neurological problems, joint aches, headaches, mood swings, and digestive problems, all of which can be explained by hypoglycemia (low blood sugar) resulting from having too much insulin. Hyperinsulinemia caused by GE yeast in gluten food products may be an alternative explanation for these symptoms.

GE Yeast Also Used to Make in Human Growth Hormone

In addition to producing human insulin, genetically engineered yeast has been created to produce human growth hormone. If these yeast enter human intestines, excessive growth hormone might be absorbed into our bloodstream, and over time this can lead to excessive body growth, arthritis,carpel tunnel syndrome, excessive snoring from enlarged throat, impaired vision, headaches, fatigue, menstrual disorders, high blood pressure, and – diabetes!
In addition to Baker's yeast, some companies, such as Eli Lilly, produce these human hormones in the bacteria E. coli, which is a common bacterium of the intestinal tract. Eli Lilly has also admitted to numerous accidental releases of their GMOs. When these microorganisms enter the digestive tract, they are eliminated in the feces. They can easily get onto peoples' hands and be spread through contact, such as handshaking and food preparation. This could make diabetes potentially contagious conditions!
People who are experiencing health issues that could be attributed to excessive insulin or growth hormone might try eliminating yeast from their diets.

BioAg Alliance Means More GMO Product Development

In the meantime, get ready for more GMO's. Since 2013, Novozymes has entered into a partnership with Monsanto, called the BioAg Alliance, to develop new GMO products. Novozymes will be responsible for production and supply of the microbial solutions to Monsanto, while Monsanto will lead field testing, registration and commercialization of all alliance products.
Novozymes has been in the farming business for some time. Yeast slurry from GE yeast production facilities at Novozymes are heat inactivated, treated with lime, and sold as the organic fertilizer, NovoGro.
"Started in the production plant in Kalundborg, Denmark, in the 1970s, Novozymes' NovoGro® organic fertilizer has successfully made its way to the US, China, and Brazil. Novozymes has worked closely together with farmers across the globe for more than 20 years supplying them with free biomass to fertilize their fields."
So, GMOs are transformed into organic fertilizer that is spread in the soil throughout the world.
This leads to concerns that antibiotic-resistant genes in the GE yeast, once applied to the soil, could spread to other microorganisms, causing antibiotic resistance, a problem in modern farming. Some studies suggest this possibility. (See Antibiotic resistance gene spread due to manure application on agricultural fields. Curr Opin Microbiol. 2011 Jun;14(3):236-43.)
However, Novozymes has conducted its own research into this possibility, and assures everyone that this is not happening. Using inactivated microbial biomass as fertilizer: the fate of antibiotic resistance genes in the environment. Res Microbiol. 2001 Nov;152(9):823-33.
But if it does happen, rest assured that there will be a new product developed to treat the problem.
Fearless Parent is the thinking parent's daily dose of non-conformist, evidence-based news about health, wellness, green living, and holistic parenting choices. Find them on FacebookTwitterPinterest, and on the air.
http://www.greenmedinfo.com/blog/genetically-modified-baker-s-yeast-spreading-obesity-and-diabetes
Photo
New Study Finds Antibiotic Resistance from GMOs in Microbes in Rivers
COMMENT by UC Berkeley microbiologist Dr Ignacio Chapela:
1. A novel method was used to select and isolate those bacteria from the river water which contained DNA suspected to derive from GMOs. These were then carefully studied to demonstrate that the DNA could not have come from other sources (e.g. mutation/natural selection).

2. Although the numbers varied, and absolute amounts of the transformed bacteria could not be measured, every river sampled was shown to contain these organisms.

3. The exact origin of the transgenic DNA incorporated into native bacterial populations was not determined. It could come from intentional releases (such as agricultural fields) or from unintentional escapes from contained situations (labs, industrial facilities).

4. These bacteria all have in common the fact that they acquired antibiotic resistance markers from transgenic origin (the markers were used to select the bacteria in the first place). Antibiotic resistance in free-living bacteria is not a good thing for those who may one day want to use antibiotics to fend-off infections (e.g. patients in hospitals).

5. Nevertheless, the antibiotic resistance is not at all the most important point of this paper (even when the authors themselves seem to think it is). Looking for antibiotic resistance was the easiest feasible way to do this work and it also has the obvious medical implications, but this is only a fraction of the many other sequences of transgenic DNA which must be expected out there in the environment, from all kinds of origins, with all kinds of possible functions. This paper is the equivalent of the proverbial sighting of the iceberg’s tip. A polaroid photo of a small part of what must be a very large and relevant phenomenon.

6. The question which beggars belief is: why is it that nobody in the “West” has been able to follow up on such leads, or even suggest doing this kind of work? One thinks of the work begun at NYU on soils, which attracted so much negative campaigning, and nary a recognition
Environ Sci Technol. 2012 Dec 18;46(24):13448-54. doi: 10.1021/es302760s. Epub 2012 Dec 6.
http://www.ncbi.nlm.nih.gov/pubmed/23215020
http://www.thelibertybeacon.com/2013/02/13/new-study-finds-antibiotic-resistance-from-gmos-in-microbes-in-rivers/

New & Not Improved Monsanto...Maui News, Ebola, RNAi Spraying Bird Sanctuary on Maui by Monsanto Corporation by Helicopter

My take is that the Ebola surgence is caused by the experimental RNAi vaccine I blogged about on July 15th 2014...The human trails took place at the same place and time as the 1st cases were reported in Africa. I mean in the same hospital and at the same time it started...

"Another interesting fact is that U.S. Centers for Disease Control owns a patent on a particular strain of Ebola known as “EboBun.” It’s patent No. CA2741523A1 and it was awarded in 2010. A patent is a form of intellectual property that allows the patent holder to control the use of a product or method of doing something. That control includes the ability to charge royalties for its use. According to Canadian patent lawyer David Schwartz, “‘You can’t patent a disease condition per se, such as cancer or influenza. But if you’re talking about patenting a life form like a bacteria or virus, if altered by man, the answer there is yes.”

If you take David Schwartz at his word, that means that the virus has to be altered or modified from it’s original chemical composition in order to be patented. That means that the strain of the virus that is currently patented was essentially created or man-made. Who better to aid in the creation of a Frankenstein vaccine for the created Ebola virus than Monsanto?"

http://covvha.net/monsanto-invests-in-ebola-virus-with-d-o-d/#.U-p1KuNdWEy



Maui News August 8, 2014...

Photo: 64 established scientists, researchers and professionals submitted an open letter to the National Academy of Science’s National Research Council (NRC), strongly criticizing the council's proposal of a panel of experts tasked with completing a new NRC study, "Genetically Engineered Crops: Past Experience and Future Prospects." More here: http://www.panna.org/scientists-challenge-makeup-panel-meant-evaluate-gmo-risks #GMOs #food #science #openletter
64 established scientists, researchers and professionals submitted an open letter to the National Academy of Science’s National Research Council (NRC), strongly criticizing the council's proposal of a panel of experts tasked with completing a new NRC study, "Genetically Engineered Crops: Past Experience and Future Prospects." 
More here:http://www.panna.org/scientists-challenge-makeup-panel-meant-evaluate-gmo-risks 

Monsanto's Experimental GMO Pesticides Are NOT HARMLESS to Migratory Birds, here is Monsanto spraying chemicals directly over Kealia National Wildlife Refuge on Maui! 
Monsanto Maui Aerial Spraying GMO Chemicals Kealia Pond National Wildlife Refuge
THIS HAS BEEN GOING ON FOR OVER 10 YEARS BY THIS SANCTUARY...
"Published on Aug 7, 2014
Kealia National Wildlife Refuge Threatened By Aerial Chemical Spraying Using Helicopters on Maui!
Monsanto Using Helicopters to Spray Herbicide on Corn/ Sugar Cane Field, cross spraying and dripping chemical into Kealia National Wildlife Refuge Ponds on Maui , Home of Rare Hawaiian Stilts.
According to the US Fish and Wildlife Service:
"About the Refuge
Headquarters
The seasonal conditions that occur at Keālia Pond National Wildlife Refuge make it a notable place for people to observe Hawai‘i's endangered wetland birds, along with a diversity of feathered visitors from as far away as Alaska and Canada, and occasionally from Asia.

Established in 1992, Keālia Pond National Wildlife Refuge encompasses approximately 700 acres and is one of the few natural wetlands remaining in the Hawaiian Islands. Located along the south-central coast of the island of Maui, between the towns of Kīhei and Mā‘alaea, it is a natural basin for a 56-square mile watershed from the West Maui Mountains.

The Keālia Coastal Boardwalk is a beautiful tranquil walkway and bird sanctuary, beside Maalaea Bay on the south edge of Maui's central valley. A walk on the boardwalk takes you through ancient wetlands where you can watch two of Hawaii's native and endangered waterbirds - the Hawaiian coot and Hawaiian stilt. Across the highway you can see Keālia Pond where waterfowl from Asia and North America come for rest and warmer climate, including northern shoveler and northern pintail. The Pacific golden plover migrates from Alaska, and other birds that come for the winter are the wandering tattler and ruddy turnstone."
According Kealia Pond National Wildlife Refuge located on Maui's south shore was established in 1992 and is part of the Maui NWR Complex. The refuge is home to endangered native water birds, and hosts migratory ducks and shorebirds in fall, winter, and spring. This refuge provides 700 acres of some of the last remaining natural wetland habitat in the State of Hawai`i. Kealia Pond is nearly 250 acres when full. The refuge is adjacent to Kealia Beach, which is a nesting ground for the endangered Hawksbill Turtle. During 2003 and 2004 a $2.6 million, 2,200 foot long boardwalk was constructed along the ocean at the Kealia Pond National Wildlife Sanctuary and allows visitors to enjoy the wetland with minimal impact to the unique habitat. The completed boardwalk has an entry area, bridge over the Kealia Pond outlet and three kiosks with interpretive displays about ecology, the biology of wetlands, endangered birds found in the refuge, turtles and humpback whales. The boardwalk overlooks Ma'alaea Bay and gives people another vantage point to see humpback whales. The bad news for those who want to try it out is that, due to snags with permits for the construction of its parking lot and a delay in completion of interpretive panels being made on the Mainland, the boardwalk is not expected to open until summer 2005.

Located at the Southern end of the central Maui isthmus and accessed from North Kihei Road between Kihei and the Wailuku - Lahaina Road. Refuge kiosk open out of nesting season, follow on site signs.

The Main Pond is located on the opposite side of the road from Ma'alea Flats, a little further along if approached from the North end. Many Hawaiian Coots and Hawaiian Stilts reside at the pond and it has one of the largest populations in the State of the latter.

The pond has an extensive list of migrants and vagrants to its name and during the winter months it usually has sizable numbers of Northern Pintail and Northern Shoveler as well as smaller numbers of Green-winged Teal, Blue-winged Teal, Lesser Scaup, Ring-necked Duck (right) and American Wigeon. Scarcer species often include Eurasian Wigeon, Garganey, Greater Scaup, Canvasback, Bufflehead and Tufted Duck. There is always the chance of something rarer, such as Redhead or Common Merganser which have occurred in the past. Geese recorded from here include White-fronted, Canada, Snow and Brant.

Ospreys are seen here almost annually and it is probably the best location in Hawai'i to see this species. Peregrine are recorded most years and Marsh Hawk has been observed on rare occasions."


https://www.youtube.com/watch?v=AgTWWau9yAE
THESE PEOPLE DO NOT CARE ABOUT YOU OR ME OR LIFE ON EARTH...

Monday, August 4, 2014

RoundUp Devastates Bees RNAi Monsanto Devastates to Extinction

A new study published in the Journal of Experimental Biology titled, "Effects of field-realistic doses of glyphosate on honeybee appetitive behavior," establishes a link between the world's most popular herbicide – aka Roundup – and the dramatic decline in honeybee (Apis mellifera) populations in North American and Europe that lead to the coining of the term 'colony collapse disorder' (CCD) in late 2006 to describe the phenomena.[1]
The researchers found that concentrations of glyphosate (GLY) consistent with the type of exposures associated with standard spraying practices in GM agricultural- and neighboring eco- systems reduced the honeybee's sensitivity to nectar reward and impaired their learning abilities – two behavioral consequences likely to adversely affect their survival abilities. Moreover, while sub-lethal doses were not found to overtly affect their foraging behavior, they hypothesized that because of their resilience, "..forager bees could become a source of constant inflow of nectar with GLY traces that could then be distributed among nest mates, stored in the hive and have long- term negative consequences on colony performance."

A Deeper Look at the New Study: Roundup Interferes with Bee Appetite and Learning

Roundup herbicide is a ubiquitous toxicant, with an accumulating body of research now showing it is a common contaminant in our airwater, rain, soil and food, and in physiologically relevant concentrations (even the part-per-trillion concentration range demonstrates endocrine disruptive and potentially carcinogenic properties) to microbial, insect, animal and human life.
When Roundup herbicide was first evaluated for toxicity to the honeybee, the focus was on acute toxicity of the 'active ingredient' and not sub-lethal and prolonged exposure effects; and certainly not the amplified toxicological synergies present in glyphosate formulations like Roundup, which when the so-called 'inert' adjuvant ingredients (e.g. surfactants) are taken into account, have been found to be at least 125 times more toxic than glyphosate alone. By only taking into account acute toxicity – as measured by the so-called LD50 (lethal dose, 50%) – on the 'active' ingredient, government regulators approved glyphosate as relatively harmless to honeybees prematurely.
The researchers expanded on the topic:
"Glyphosate [GLY] toxicity tests on Apis mellifera for product approval did not consider sub-lethal nor prolonged exposure effects. Studies were only focused on obtaining LD50 (lethal dose, 50%) as a measure of the effect of an acute exposure, but nevertheless, they were carried out on the basis that honeybees might in fact be exposed to GLY in their natural environment, either through the consumption of contaminated resources or through a direct exposure as a result of inadvertent spraying (Giesy et al., 2000). Even though LD50 results seem to indicate that GLY is not harmful for honeybees, the fact that honeybees are potentially exposed to GLY motivated us to pursue further analysis and to address the lack of chronic studies."
The authors of the new study set out to test whether doses of glyphosate bees would realistically encounter in the field (field-realistic doses) could affect their feeding behavior (appetitive behavior) in a deleterious manner.
They exposed honeybees to field-realistic doses of glyphosate chronically and acutely, and observed: "a reduced sensitivity to sucrose and learning performance for the groups chronically exposed to GLY concentrations within the range of recommended doses," as well as significant decrease in elemental learning, non-elemental associative learning, and short-term memory retention, when exposed to acute GLY doses.

Roundup Already Identified As Likely Cause of Colony Collapse Disorder

This latest study is not the first to link glyphosate to the vanishing honeybee.
Extensive research on the topic performed by Dr. Don D. Huber and summarized in an article published last year titled, "Is glyphosate a contributing cause of bee colony collapse disorder (CCD)?," lead him to conclude that the 880 million pounds of glyphosate released into the environment worldwide has been contributing to the collapse of the honeybee. The paper revealed the following six ways that glyphosate could contribute to CCD:

  • Glyphosate chelates minerals, lowers nutrients in plants: In CCD, Malnutrition is universally present.
  • Glyphosate acts like an antibiotic to beneficial bacteria: In CCD, loss of Lactobacillus and other critical beneficial bacteria for digestion is commonly observed.
  • Glyphosate is a neurotoxin: In CCD, honeybees experience neurological changes associated with disorientation.
  • Gyphosate causes endocrine hormone & immune disruption: In CCD, immunity and other hormonal variables are altered or suppressed.
  • Glyphosate stimulates fungal overgrowth: In CCD, the fungal pathogen Nosema increases.
  • Glyphosate persists and accumulates: High environmental exposure, including glyphosate residues present in honey, nectar and other plant products, make honeybees susceptible to continual toxic challenge -- which is believed to be a primary underlying cause of CCD.
  • Other Factors Contributing to Colony Collapse

  • While it is now increasingly acknowledged that many agrochemicals pesticides -- especially neonicotinoids -- are toxic to honeybees, there are other factors that likely play a role as well:
    It should be pointed out that the last factor listed – infectious organisms – are likely more a symptom than a cause of honeybee morbidity and mortality. In other words, following electromagnetic, agrochemical and dietary assault, the immune system of the honeybee – and the collective immunity of the hive – weakens, leading to greater susceptibility to opportunistic infections.
    One USDA study published in 2013 discussed the role of fungicidal contaminants in pollen leading to increased probability of Nosema fungal infection in bees who consumed pollen with a higher fungicide load.[3]
    This linkage between chemical exposure > immune suppression, > opportunistic infection, is especially poignant when it comes to Roundup herbicide, which profoundly alters the makeup of the beneficial flora in exposed organisms, leading to the overgrowth of pathogenic bacteria. A 2012 PloS study found that lactic acid bacteria living in the crop (the part of the bee's alimentary canal that stores food prior to digestion) of bees are vitally important for the health of honeybees, with some strains suggesting a history of association with bees stretching over 80,000,000 years ago. Various chemical are capable of damaging this vitally important locus for the honeybee's immunity and digestion, and are likely exerting their adverse effects through sublethal, hard to detect mechanisms.
  • Why Does Monsanto Own Beelogics, 'The Guardian of Bee Health Worldwide'?

    On Sept. 28th, 2011, Monsanto announced that it was acquiring the company Beeologics, whose explicit goal is to become "the guardian of the bee health wordwide," including finding ways to address CCD.
    Here is their mission statement:

    "Beeologics LLC is an international firm dedicated to restoring bee health and protecting the future of honey bee pollination. Beeologics' mission is to become the guardian of bee health worldwide. Through continuous research, scientific innovation, and a focus on applicable solutions, Beeologics is developing a line of RNAi-based products to specifically address the long-term well being of honey bees, including the control of parasites and how they're involved in Colony Collapse Disorder (CCD)."
    A classical problem-solution approach, Monsanto creates a problem – a systemic herbicide intended to 'save the world' from hunger as part of its GMO Roundup-ready proprietary production system that actually destroys the pollinators required to maintain our global food supply – and then capitalizes on a GM solution on the backend, with patented RNA interference 'solutions' intended to, again, 'save the world' from hunger.

    I tried to just quote the article, but it is TOO IMPORTANT!Sayer Ji is the founder of GreenMedInfo.com, an author, educator, Steering Committee Member of the Global GMO Free Coalition (GGFC), and an advisory board member of the National Health Federation. 

    He founded Greenmedinfo.com in 2008 in order to provide the world an open access, evidence-based resource supporting natural and integrative modalities. It is widely recognized as the most widely referenced health resource of its kind.

    PLEASE READ ABOUT RNAi...it will be the turning point to the END!

    Saturday, July 26, 2014

    Pesticide Linked to 3 Generations of Disease: Methoxychlor Causes Epigenetic Changes

    Washington State University researchers say ancestral exposures to the pesticide methoxychlor may lead to adult onset kidney disease, ovarian disease and obesity in future generations.
    “What your great-grandmother was exposed to during pregnancy, like the pesticide methoxychlor, may promote a dramatic increase in your susceptibility to develop disease, and you will pass this on to your grandchildren in the absence of any continued exposures,” says Michael Skinner, WSU professor and founder of its Center for Reproductive Biology.
    He and his colleagues document their findings in a paper published online in PLOS ONE. The study was funded by the National Institutes of Health.
    DDT replacement banned in 2003
    Methoxychlor—also known as Chemform, Methoxo, Metox or Moxie—was introduced in 1948 and widely used during the 1970s as a safer replacement for DDT. It was used on crops, ornamental plants, livestock and pets. It is still used in many countries around the world.
    It was banned in the U.S. in 2003 due to its toxicity and ability to disrupt endocrine systems. Methoxychlor can behave like the hormone estrogen and profoundly affects the reproductive system.
    Supports earlier epigenetic findings
    When Skinner and his colleagues exposed gestating rats to methoxychlor at a range typical of high environmental exposures, they saw increases in the incidence of kidney disease, ovary disease and obesity in offspring spanning three generations. The incidence of multiple diseases increased in the third generation or “great-grandchildren.”
    The researchers say the pesticide may be affecting how genes are turned on and off in the progeny of an exposed animal, even though its DNA and gene sequences remain unchanged.
    This is called transgenerational epigenetic inheritance. In recent years, the Skinner lab has documented epigenetic effects from a host of environmental toxicants, including DDT, plastics, pesticides, fungicides, dioxins, hydrocarbons and the plasticizer bisphenol-A or BPA. The newest findings support those observations.
    Implications for obesity, fertility, disease
    The work is also the first to show that a majority of transgenerational disease traits can be transmitted primarily through the female line.
    Additionally, the study identified mutations in the sperm epigenome of great-grandchild male rats. The epigenome functions like a set of switches for regulating gene expression and can be altered by environmental conditions.
    The epigenetic changes observed were specific to methoxychlor exposure and may prove to be valuable biomarkers for future research on transgenerational disease.
    For people exposed to the pesticide, Skinner says his findings have implications such as reduced fertility, increased adult onset disease and the potential to pass on those conditions to subsequent generations.
    He suggests that ancestral exposures to methoxychlor over the past 50 years in North America may play a part in today’s increasing rates of obesity and disease.
     BY FRACTURED PARADIGM – JULY 25, 2014 POSTED IN: PESTICIDES & HERBICIDES  

    Read more: Pesticide Linked to 3 Generations of Disease: Methoxychlor Causes Epigenetic Changes http://fracturedparadigm.com/2014/07/25/pesticide-linked-to-3-generations-of-disease-methoxychlor-causes-epigenetic-changes/#ixzz38eovBJgu

    US Experts Push Congress to Reject Toxic Herbicide Mix ‘Enlist Duo’

    Prominent doctors, scientists and business leaders today urged Congress to pressure the Obama administration to reject an application to market “Enlist DuoTM,” a new toxic herbicide mix of 2,4-D and glyphosate.
    enlist duo
    The Environmental Protection Agency is currently reviewing an application from Dow AgroSciences, a wholly owned subsidiary of Dow Chemical Co., to sell Enlist Duo for use in agriculture. Enlist Duo would be used on millions of acres of farm fields in combination with a new type of herbicide-resistant, genetically engineered crops.
    The medical and scientific experts told a Congressional briefing that this would put human and environmental health at risk.
    The U.S. Department of Agriculture is weighing a separate application from Dow to market corn and soybean seeds that the company genetically engineered to tolerate the 2,4-D/glyphosate combination.
    Those who spoke at the briefing to oppose Dow’s application included Dr. Philip Landrigan of Mount Sinai School of Medicine, Dr. Catherine Thomasson of Physicians for Social Responsibility, John P. Wargo, Ph.D. of Yale University, Doug Gurian-Sherman, Ph.D. of Center for Food Safety and Gary Hirshberg of Stonyfield Farm and the advocacy group Just Label It.
    “Exposures to herbicides in early life can lead to disease in childhood or disease later on in adult life or even old age,” said Dr. Landrigan, dean for global health at Mount Sinai School of Medicine. “Herbicide chemicals can also cross from mother to child during pregnancy and prenatal exposures that occur during the nine months of pregnancy are especially dangerous.”
    “Physicians are very concerned about exposure to the combination of 2,4-D and glyphosate because of the potential lifelong and irreversible effects on the health of vulnerable populations, including children, pregnant women and farm workers,” said Dr. Thomasson, executive director of Physicians for Social Responsibility. “Policy decisions should take into account the costs that can result from failure to act on the available data on toxic herbicides.”
    Americans are already exposed to 2,4-D in herbicides applied to lawns, turf grass and other non-agricultural sites. Exposure to the toxic defoliant has been linked to non-Hodgkin lymphoma and Parkinson’s disease as well as immune system, thyroid and reproductive problems. Glyphosate is the harmful active ingredient in Roundup, the infamous weed killer developed by chemical giant Monsanto.
    “2,4-D already is permitted by EPA to remain as residues on over 300 different forms of food,” said John P. Wargo, Ph.D., professor of environmental health and politics at Yale University. “Spraying millions of additional acres with these chemicals will increase their contamination of soils, surface and groundwater and foods bearing their residues. If applied by aircraft, sprays will drift to adjacent lands, potentially endangering those who reside, go to school or work nearby.”
    Crops genetically engineered to withstand Roundup were introduced in the mid-90s. As scientists predicted, weeds quickly developed resistance to the herbicide, which in turn led to the use of hundreds of millions more pounds of the weed killer than would have occurred without these crops.
    “The toxic herbicide mix is being proposed because glyphosate alone is no longer working, since its overuse has led to the development of herbicide-resistant ‘superweeds’,” said Gary Hirshberg, chairman of Stonyfield Farm and Just Label It. “This ‘chemical treadmill’ benefits the GE patent holders at the expense of farmers, human health and the environment.”
    “The biotech industry is about to repeat the same mistakes that got us into this predicament,” said Doug Gurian Sherman, Ph.D, senior scientist with Center for Food Safety. “The public must demand policies and research that help farmers adopt proven, ecologically-based farming systems with minimal pesticide use that are productive, profitable and better for society.”
    In June, 35 doctors, scientists and researchers, including Dr. Chensheng (Alex) Lu of Harvard School of Public Health and Dr. Raymond Richard Neutra, a retired division chief of the California Department of Public Health, sent a letter to EPA Administrator Gina McCarthy urging her to deny Dow’s application.
    Before the public comment period ended, EPA received half a million comments opposing the controversial proposal.
    “The risks of approving a new 2,4-D mixture are clear,” said Mary Ellen Kustin, senior policy analyst at the Environmental Working Group. “If approved, the use of 2,4-D would increase three-to-sevenfold by 2020, according to the USDA. The risks are too great and benefits too few to jeopardize public health and the environment.”

    Dioxin So Bad USA and NZ Pretend No Problem

    Seventy-five different Dioxins have been identified, each with its own chemical structure and a unique toxicity.[4] Large groups of related compounds such as polycholorinated biphenyls (PCB) and dibenso furans, have similar affects. Several of these dioxins in various amounts were present within the various herbicides sprayed in Vietnam. The worst and most toxic dioxin, 2,3,7,8-Tetrachlorodibenzo-p-dioxin (abbreviated as TCDD), was a chemical contaminant found in over 11 Million gallons of Agent Orange. The supposed trace amounts of TCDD are estimated at 170 kilograms and represents the largest dioxin release in history.[4] Environmental Protection Agency in its recently completed re-evaluation of its 1994 report on Dioxin, reported data that strongly supports the dangers of dioxin yet it stopped short of initiating or banning products containing dioxin.[12] This work did suggest the potential for a very high risk in the general population if it occurred on the order of 1 in 10,000 to 1 in 1000.[12,34,52]
    http://vvi.org/Content/mjournal.asp

    Photo: The Agent Orange manufactured by Monsanto contained 2,3,7,8-tetrachlordibenzo-para-dioxin (TCDD), extremely deadly even when measured against other dioxins. The levels found in domestic 2,4,5-T were around 0.05 ppm, that shipped to Vietnam peaked at 50 ppm, ie 1,000 times higher than the norm. ( NORM???? or considered a safe level...?)

#monsanto #dow #maui #hawaii #biotech #molokai

http://www.whale.to/a/monsanto_h.html
    The Agent Orange manufactured by Monsanto contained 2,3,7,8-tetrachlordibenzo-para-dioxin (TCDD), extremely deadly even when measured against other dioxins. The levels found in domestic 2,4,5-T were around 0.05 ppm, that shipped to Vietnam peaked at 50 ppm, ie 1,000 times higher than the norm. ( NORM???? or considered a safe level...?)
    http://www.whale.to/a/monsanto_h.html

    Kimberly Usher's photo.
    "In Vietnam they have found levels of 30 to 108 parts per trillion in blood," he said. "Levels in Maori women around the Bay of Plenty, where the herbicide was extensively sprayed, have already been found to be up around 26.7ppt. As of yet we still don’t know what the blood levels are in New Plymouth."

    Gibbs says even burning the waste didn’t destroy it. Instead waste streams left residue in the soil, on washing hanging out to dry and on barbecues. "We ate it, breathed it and wore it. When the Yanks burnt it off after Vietnam they burnt it off 80-90 miles down wind from Johnson Island.

    "We burnt ours downwind on the whole town of New Plymouth. In the 1987 enquiry they said they found no evidence of dioxin in people or soil. But what they had was a 1,500 ppt safe level. The highest recorded in Vietnam was 808 ppt. In New Plymouth we’ve already levels up to 310 ppt." His views may be ignored by health officials in New Zealand, but they have found credence in America. George Lucier, director of the National Toxicology Programme, and author of the Environmental Protection Agency report, says there is no avoiding dioxin.

    "Even penguins in Antarctica have dioxin in them. No-one sets out purposely to make dioxin. It is an unwanted side-product that you get from burning. Anytime you combine heat, chlorine and organic material, there is the possibility of making dioxins."

    Lucier says scientists did not quite understand how dioxin damaged the body, but did know it acted on a universal mechanism controlling cell functions.

    Dioxin attaches, or binds tightly, to the AII receptor - a kind of cellular doorway found in virtually all cells in the body. Once there, it changes the function of hundreds of genes. It will either stimulate gene expression of suppress it.

    Dioxin exposure has been linked to many different tumours, especially non-Hodgkin’s lymphoma, respiratory cancers, soft tissue sarcoma and prostate cancer. One Italian study of dioxin in children found hormonal changes.

    "When they have children, most or all their kids are girls, not boys," says Lucier. "Dioxin affects pathways that are involved in normal growth and differentiation, so it can cause birth defects," he adds. "It can effect sperm counts."

    Drake thought the new Labour government, with its Green allies, would order a fresh enquiry following new American evidence on the damaging effects of dioxin. Instead, he says, they are happy to sweep the issue under the carpet. In June of this year Health Minister Annette King refused calls for a new enquiry, relying on conclusions found in 1986 – interestingly a report delivered under the previous Labour Government."

    The enquiry team concluded that there was no evidence of major contamination in New Plymouth or of any major health risk Yet residents say that part of the information used in that research was based on American studies which have since found to be fraudulent. This is where the issue becomes more complicated. In 1949 an explosion at the Monsanto chemical plant in Nitro, West Virginia, exposed many workers to effects of 2,4,5-T. Thirty years later Monsanto scientists and an independent researcher, Dr Raymond Sunkind, compared death rates amongst workers exposed to 2,4,5-T to those who hadn’t been exposed. When no differences between the two groups were found, Monsanto claimed that dioxin did not cause cancer. Evidence of inaccuracies were only exposed in the late 1980s when a group of Missouri citizens sued Monsanto for alleged injuries suffered during a chemical spill caused by a train derailment in 1979. While reviewing documents obtained from Monsanto, it was held in court that during the early studies, scientists omitted five deaths from the dioxin-exposed and put them in the unexposed group. Given that, and the leaked report to the Washington Post, it’s small wonder that the residents are now calling for a new inquiry.
    THE POISONING OF NEW ZEALAND
    http://www.investigatemagazine.com/poisoning_of_new_zealand%20OCT2000.htm

    Photo: The controversial GMO banana, funded by the Bill & Melinda Gates Foundation and being grown in Australia, has arrived in the U.S. for human feeding trials. Volunteers will be paid $900 to participate in this feeding trial, which will analyze blood samples to measure the impact on vitamin A levels before and after eating. Wendy White, the researcher at Iowa State University who is carrying out the study, is reluctant to discuss it. In an e-mail to NPR, she wrote that disclosing details about the study "could preclude me from publishing our findings in a peer-reviewed scientific journal." This leads us to ask several questions. First, why the secrecy? Second, what is the duration of the study - will it be a meaningful long term study? Third, will the study meet the criteria for a chronic toxicity study or will it only measure vitamin A levels? Lastly and most importantly, Americans have been involuntarily participating in GMO feeding trials without our knowledge or consent for almost 20 years. WHERE'S OUR MONEY????

READ: http://www.npr.org/blogs/thesalt/2014/07/08/325796731/globe-trotting-gmo-bananas-arrive-for-their-first-test-in-iowa

#GMO #Banana #HumanFeedingTrials #USA #Uganda #Australia #BillAndMelindaGates #GatesFoundation #MelindaGatesFoundation #VitaminA #labelgmos #boycottgmos #bangmos #GMOFreeCanada #GMOFreeUSA