Tuesday, January 12, 2016

Dealing w/Pesticides w/Effects w/Science from 1993

Pesticide Poisoning is Cholinesterase Inhibition...100%

"Any pesticide that can bind, or inhibit, cholinesterase, making it unable to breakdown acetylcholine, is called a "cholinesterase inhibitor," or "anticholinesterase agent." ..Every person has his/her own individual 'normal' range of baseline cholinesterase values; cholinesterase levels vary greatly within an individual, between individuals, between test laboratories, and between test methods.

The extent of potential pesticide poisoning can be better understood if cholinesterase tests taken after exposure to the cholinesterase inhibiting pesticides can be compared to the individual's baseline, pre-exposure measurement...
(IMO Everyone who moves to an area known to be toxic should have a baseline reading beforehand. I've NEVER had this reading as doctors refuse to acknowledge my pesticide poisoning...Even though I repeat it over, and over at every office visit. And... I've been through 50 doctors in my 4 major poisonings already, since 1995.)

The two main classes of cholinesterase inhibiting pesticides are the organophosphates (OPs) and the carbamates (CMs). Some newer chemicals, such as the chlorinated derivatives of nicotine can also affect the cholinesterase enzyme.

Organophosphate insecticides include some of the most toxic pesticides. They can enter the human body through skin absorption, inhalation and ingestion. They can affect cholinesterase activity in both red blood cells and in blood plasma, and can act directly, or in combination with other enzymes, on cholinesterase in the body."

Howz this? "OVEREXPOSURE"...WT? 
Who do think they are kidding here? 
Similar to " pesticide does not harm people" lie.
This study is over 22 years old...
USDA has recently raised the allowable levels...3000%...
Exactly what was the point of doing that? 
For our health??

"Overexposure to organophosphate and carbamate insecticides can result in cholinesterase inhibition. These pesticides combine with acetylcholinesterase at nerve endings in the brain and nervous system, and with other types of cholinesterase found in the blood. This allows acetylcholine to build up, while protective levels of the cholinesterase enzyme decrease. The more cholinesterase levels decrease, the more likely symptoms of poisoning from cholinesterase inhibiting pesticides are to show."

"symptoms can be confused with influenza (flu), heat prostration, alcohol intoxication, exhaustion, hypoglycemia (low blood sugar), asthma, gastroenteritis, pneumonia, and brain hemorrhage. This can cause problems if the symptoms of lowered cholinesterase levels are either ignored or misdiagnosed as something more or less harmful than they really are.
The types and severity of cholinesterase inhibition symptoms depend on:

  1. the toxicity of the pesticide.
  2. the amount of pesticide involved in the exposure.
  3. the route of exposure.
  4. the duration of exposure."
"When symptoms of decreased cholinesterase levels first appear, it is impossible to tell whether a poisoning will be mild or severe. In many instances, when the skin is contaminated, symptoms can quickly go from mild to severe even though the area is washed. Certain chemicals can continue to be absorbed through the skin in spite of cleaning efforts."

"Ideally, a pre-exposure baseline cholinesterase value should be established for any individual before they come in regular contact with organophosphates and carbamates. Fortunately, the breakdown of cholinesterase can be reversed and cholinesterase levels will return to normal if pesticide exposure is stopped.


Humans have three types of cholinesterase: red blood cell (RBC) cholinesterase, called "true cholinesterase;" plasma cholinesterase, called "pseudocholinesterase;" and brain cholinesterase. Red blood cell cholinesterase is the same enzyme that is found in the nervous system, while plasma cholinesterase is made in the liver.When a cholinesterase blood test is taken, two types of cholinesterase can be detected. Physicians find plasma cholinesterase readings helpful for detecting the early, acute effects of organophosphate poisoning, while red blood cell readings are useful in evaluating long-term, or chronic, exposure (8).
The cholinesterase test is a blood test used to measure the effect of exposure to certain or cholinesterase-affected insecticides. Both plasma (or serum) and red blood cell (RBC) cholinesterase should be tested. These two tests have different meanings and the combined report is needed by the physician for a complete understanding of the individual's particular cholinesterase situation.
Laboratory methods for cholinesterase testing differ greatly, and results obtained by one method cannot be easily compared with results obtained by another. Sometimes there is also considerable variation in test results between laboratories using the same testing method. Whenever possible, cholinesterase monitoring for an individual should be performed in the same laboratory, using a consistent testing method."

I can hardly believe this was put into the article!RIGHT HERE IS GROUNDS TO PUT THEM ALL OUT OF BUSINESS!

"...factors should be considered in deciding how often someone should have his/her cholinesterase levels tested:...
D. The past safety record of a company and the work history and experience of an individual."

Publication Date: 9/93
A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Michigan State University, Oregon State University, and University of California at Davis. Major support and funding was provided by the USDA/Extension Service/National Agricultural Pesticide Impact Assessment Program.

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