Friday, July 31, 2015

GMO Risk Analysis Non-Existent~ Prediction ~ Failure and we all DIE!

Proliferating GMOs could lead to “an irreversible termination of life [on] the planet.”
Risk analyst Nassim Nicholas Taleb predicted the 2008 financial crisis, by pointing out that commonly-used risk models were wrong. Now he points out that most boosters for genetically modified foods (GMOs) – including scientists – are totally ignorant about risk analysis.

Risk analyst Nassim Nicholas Taleb predicted the 2008 financial crisis, by pointing out that commonly-used risk models were wrong.  Taleb – a distinguished professor of risk engineering at New York University, and author of best-sellers The Black Swan and Fooled by Randomness – Taleb became financially independent after the crash of 1987, and wealthy during the 2008 financial crisis.
Taleb noted last year that most boosters for genetically modified foods (GMOs) – including scientists – are totally ignorant about risk analysis.   Taleb said that proliferating GMOs could lead to “an irreversible termination of life [on] the planet.”

This month, Taleb – and tail-hedging expert Mark Spitznagel, who also made a hugely profitable billion dollar derivatives bet on the stock market crash of 2008 – wrote in the New York Times:
Before the crisis that started in 2007, both of us believed that the financial system was fragile and unsustainable, contrary to the near ubiquitous analyses at the time.

Now, there is something vastly riskier facing us, with risks that entail the survival of the global ecosystem — not the financial system. This time, the fight is against the current promotion of genetically modified organisms, or G.M.O.s.

Our critics held that the financial system was improved thanks to the unwavering progress of science and technology, which had blessed finance with more sophisticated economic insight. But the “tail risks,” or the effect from rare but monstrously consequential events, we held, had been increasing, owing to increasing complexity and globalization. Given that almost nobody was paying attention to the risks, we set ourselves and our clients to be protected from an eventual collapse of the banking system, which subsequently happened to the benefit of those who were prepared.


We were repeatedly told that there was evidence that the system was stable, that we were in “the Great Moderation,” a common practice that mistakes absence of evidence for evidence of absence. For the financial system to be viable, the solution is for it to resemble the restaurant business: decentralized, with mistakes that stay local and that cannot bring down the entire apparatus.
Indeed, a Nobel prize-winning economist and many other experts say that too much centralization destabilizes economies and other systems.

Taleb and Spitznagel by pointing out that the GMO-cheerleaders are making the same anti-scientific arguments as those who said the financial system was stable prior to 2008:
The financial system nearly collapsed, but it was only money. We now find ourselves facing nearly the same five fallacies for our caution against the growth in popularity of G.M.O.s.  [Nearly 80% of all food produced in the U.S. contains GMOs.]

First, there has been a tendency to label anyone who dislikes G.M.O.s as anti-science — and put them in the anti-antibiotics, antivaccine, even Luddite category. There is, of course, nothing scientific about the comparison. Nor is the scholastic invocation of a “consensus” a valid scientific argument.

Interestingly, there are similarities between arguments that are pro-G.M.O. and snake oil, the latter having relied on a cosmetic definition of science. The charge of “therapeutic nihilism” was leveled at people who contested snake oil medicine at the turn of the 20th century. (At that time, anything with the appearance of sophistication was considered “progress.”)

Second, we are told that a modified tomato is not different from a naturally occurring tomato. That is wrong: The statistical mechanism by which a tomato was built by nature is bottom-up, by tinkering in small steps (as with the restaurant business, distinct from contagion-prone banks). In nature, errors stay confined and, critically, isolated.

Third, the technological salvation argument we faced in finance is also present with G.M.O.s, which are intended to “save children by providing them with vitamin-enriched rice.” The argument’s flaw is obvious: In a complex system, we do not know the causal chain, and it is better to solve a problem by the simplest method, and one that is unlikely to cause a bigger problem.

Fourth, by leading to monoculture — which is the same in finance, where all risks became systemic — G.M.O.s threaten more than they can potentially help. Ireland’s population was decimated by the effect of monoculture during the potato famine. Just consider that the same can happen at a planetary scale.
We noted in 2009:
It has been accepted science for decades that when all the farmers in a certain region grow the same strain of the same crop – called “monoculture” – the crops become much more susceptible.


Because any bug (insect or germ) which happens to like that particular strain could take out the whole crop on pretty much all of the region’s farms.

For example, one type of grasshopper – called “differential grasshoppers” – loves corn. If everyone grows the same strain of corn in a town in the midwest, and differential grasshoppers are anywhere nearby, they may come and wipe out the entire town’s crops (that’s why monoculture crops require such high levels of pesticides).

On the other hand, if farmers grow a lot of different types of crops (“polyculture”) , then a pest might get some crops, but the rest will survive.
Taleb and Spitznagel conclude:
The G.M.O. experiment, carried out in real time and with our entire food and ecological system as its laboratory, is perhaps the greatest case of human hubris ever. It creates yet another systemic, “too big too fail” enterprise — but one for which no bailouts will be possible when it fails.
In the real world – using statistical analysis – GMOs are inferior when compared to other types of food, because GMOs are associated with:
Source: Washington’s Blog


We either respect the Tree of Life or exterminate ourselves...

GMO Double Talk

Reading science articles submitted to Science journals is very boring...after a while you can actually understand the jargon, and see how they use word changes to cover themselves...also to kiss the butts of those who fund them...
Like this...Playing up the false need for GMOs in the beginning of the article.
"The effects of uncontrolled population growth have produced a series of looming crises that not only have biology at their base but also present an arena in which practitioners of the biological sciences will be critical contributors. The analyses that emerged from the NAS study (National Research Council Committee, 2009) identified four areas in which biology is poised to make pivotal contributions: (1) the provision of food for the growing population; (2) the development of alternative energy sources; (3) the promotion of health; and (4) environmental protection."

But...then by the end issues a subtle warning against doing so...
..."The study of biochemical adaptations in animals and plants, which does integrate across the hierarchy, requires focusing on a few relevant levels (Fig. 3B)."

..."(B) In animals and plants, the level of the organism has a series of defining lower levels that reflect their multicellularity. While most fields of biology focus on one level or contiguous levels, an animal or plant's ecology can be studied by characterizing its biochemical adaptations to the environment in which it evolved (green arrows), an area of emphasis developed by Hochachka and Somero."

..."In addition to being evolutionarily basal and having a simplified hierarchy of life, microbes also have certain traits that, when considered, provide insight into the fundamental capacities and limitations of life processes. Relevant to the discussion here is the widespread occurrence of horizontal gene transfer (HGT) in the Bacteria (Darmon and Leach, 2014) and Archaea (Wolf et al., 2012), and their metabolic diversity (Kluyver and van Niel, 1956) (Fig. 4). While concepts of evolutionary selection, as developed by Darwin, apply to both microbiological and macrobiological organisms, the Mendelian vertical inheritance of traits and associated genetic patterns is largely restricted to groups within the Eucarya and, as such, is a derived feature. Further, the propensity for HGT seems to have attenuated in the radiation of the Eucarya, particularly among the animals, although evidence is increasing that it is more prevalent than previously thought (Boto, 2014). Because we now know that the most common mode of acquisition of traits occurs by HGT in Bacteria and Archaea, we can no longer use the ‘Modern Synthesis’ to describe the genetic basis of evolution. With this change in perspective, Koonin has suggested that we need a ‘Post-Modern Synthesis’ that encompasses the genetic mechanisms of all branches of the Tree of Life (Koonin, 2012; Koonin and Wolf, 2012). Along with the relative instability of their genome, a defining theme in microbes is their metabolic diversity. "

..."The array of microbial metabolisms includes all the known ways in which organisms can obtain carbon (autotrophy or heterotrophy), reducing equivalents (lithotrophy or organotrophy), and energy (phototrophy or chemotrophy), and they combine these in nearly every way possible. These metabolic strategies use a wide variety of terminal electron donors and acceptors. By definition, the acquisition of the mitochondrion is the hallmark characteristic of the Eucarya; this innovation nevertheless has almost exclusively limited the Eucarya to oxygen as a terminal electron acceptor for respiration."

..."Another byproduct of advances in sequencing technology has been the recognition that intimate animal and plant interactions with microbes are now, as they have been throughout geological history, a common theme among life forms. With the seminal work of Lynn Margulis, biologists became aware that the eukaryotic cell arose through a symbiotic event (Sagan, 1967). Interestingly, this event, i.e. the acquisition of the mitochondrion, appears to have occurred once and spurred the radiation of all of the Eucarya (Lane, 2014). The presence of mitochondria augmented the efficiency of cellular bioenergetics by increasing the membrane surface area for the production of ATP through cellular respiration. In addition, over evolutionary history, much of the mitochondrial genome has been transferred to the nucleus, such that the mitochondria energetically support the much larger nuclear genome. These relationships between the nucleus and mitochondria of the cell provide eukaryotes with orders of magnitude more energy per gene than is available per gene for the Bacteria and Archaea (Lane, 2014). In addition to its well-recognized role as the ‘powerhouse’ of the cell, recent studies have indicated that the mitochondria control many more cellular functions (Mitra and Lippincott-Schwartz, 2010; Antico Arciuch et al., 2012; Friedman and Nunnari, 2014). For example, the mitochondrial network in the cell appears to be electrically coupled (De Giorgi et al., 2000) and coordinates such critical processes as cell death, cell proliferation, autophagy (Rambold and Lippincott-Schwartz, 2011), cell differentiation (Mitra et al., 2012) and aging (Lee and Wei, 2012). The view seems to be emerging that perhaps the mitochondrial network is actually the ‘brains’ of the cell, controlling much of the cell's processes, including activities of the nucleus.

Whereas biologists have known for decades about the endosymbiotic origin of the eukaryotic cell, intimate interactions of microbes with animals and plants had been thought to be rare and restricted to only a few groups. The recent, technology-enabled ability to identify and characterize uncultured microbial cells occurring in large communities has demonstrated that most animals and plants rely on interactions with microbes (Hadfield, 2011; Gilbert et al., 2012; McFall-Ngai et al., 2013). This dependence is not surprising, given that the differences in characters between microbiological and macrobiological forms (Fig. 4) render them complementary, i.e. by forming alliances they increase one another's scope. To date, over half of the nearly 40 animal phyla have members in which symbiotic associations have been described, with the most speciose third all having representatives with such alliances "

.."Among all of the animal–microbe interactions studied over the past 20 years, the human microbiota continues to receive the most attention. Researchers have identified stable, predictable communities associated with several sites on the body, including the skin and the digestive, respiratory, excretory and reproductive tracts. These communities have been studied in health and disease over the trajectory of ontogeny. Because the data have determined that the microbiota is a central player in the biology of humans,"

..."The expansion of the field into this frontier would usher in the study of how the integrated activities of the resident two or three domains of life, i.e. the holobiont (Gilbert, 2014), are coordinated in the metaorganism in responses to various environmental pressures. Thus, as we go forward in the study of the mechanisms underlying the biochemical adaptations of animals, let's not forget their microbes!"

Giving microbes their due – animal life in a microbially dominant world
Margaret J. McFall-Ngai*

Traits of the microbiological and macrobiological worlds that promote their partnering intimate association. Picture.

Depleted Soil, Food, Body~ Nutrients to Complete Life Cycle ~Monsanto etal

Vitamins and minerals are not functionally separable. They make each other work.

Mineral deficiencies can cause vitamin deficiencies, and vice versa. Epidemic mineral deficiency in America is a well-documented result of systematic soil depletion. So that is the other prime difference between whole food vitamins and synthetics: whole food vitamins contain within them many essential trace minerals necessary for their synergistic operation.

Synthetic vitamins contain no trace minerals, relying on, and depleting, the body’s own mineral reserves.

Following the German agricultural methods of Von Leibig in the mid-1800s, American farmers found that NPK (nitrogen, phosphorus, and potassium) was all that was necessary for crops to look good.
As long as NPK is added to the soil, crops can be produced and sold year after year from the same soil. They look OK. But the trace minerals vital for human nutrition are virtually absent from most American soil after all these years. Many of these minerals, such as zinc, copper, and magnesium, are necessary co-factors of vitamin activity.

Depleted topsoil is one simple, widespread mechanism of both vitamin and mineral deficiency in American produce today. This doesn’t even take into account the tons of poisonous herbicides and pesticides dumped on crops.
American agri-business has one motive: profit. Such a focus has resulted in an output of empty produce and a nation of unhealthy people. The earth’s immune system is its soil. To be vital and capable of growing vital foods, soil must be rich in both minerals and soil-based organisms – life forms. Healthy produce naturally resists insects. Insects are like bad bacteria in the body: they are attracted to diseased tissue, though they do not cause it.

Sunday, August 11, 2013

“Stunning” Difference of GM from non-GM Corn" ~Formaldehyde~ ~NO NUTRITION~

A comparison of US Midwest non-GM with GM corn shows shockingly high levels of glyphosate as well as formaldehyde, and severely depleted of mineral nutrients in the GM corn Dr Mae-Wan Ho
The results of a comparison of GM and non-GM corn from adjacent Midwest fields in the US in Table 1.
Table 1   Comparison between GM and non-GM corn grown side by side*

Parts per million (ppm)
IngredientGM cornNon-GM corn

Calcium146 130

*The GM corn was grown in a field that has been no-till, continuous GM corn (Roundup Ready) for 5-10 years and with a glyphosate herbicide weed control regime for all of the 10 years. The Non-GM corn has not had glyphosate (or Roundup) applied to the field for at least five years. The GM corn test weight was 57.5 lb; and non-GMCorn test weight 61.5 lb.

Microbe Biodome Gut Punch to Monsanto

Horizontal Gene Transfer in the done by the microbes in our stomach...
Only microbes split and combine with each other...
Plants and animals do gene transfer, Having a baby or producing a seed...
My conclusions are that GMOs really do influence in a chaotic and uncontrollable way our gut bacteria; essentially taking over and destroying our microbial genome individually...
This will also include environmental toxins, like pesticides, and any chemical we touch or ingest. 
These GMO Bio Toxins or BT are HGT of our plants that are new microbes in themselves that can recombine with our own natural microbes...This is how we make our stomach a pesticide factory...That we will never be able to adapt to...One cannot adapt to DEATH...Only remove one's self from it occurring...We are life creatures...Not creatures of death.

Where are all the studies showing our microdome pesticide factory at?
 Maybe this is it...Little old me showing it...Using others data!

In this article, Comparative Metagenomics Revealed Commonly Enriched Gene Sets in Human Gut Microbiomes, I did a search for horizontal gene transfer (HGT) By using the word horizontal, and HGT.

..."In addition, we discovered a conjugative transposon family explosively amplified in human gut microbiomes, which strongly suggests that the intestine is a ‘hot spot’ for horizontal gene transfer between microbes."

..."Although this remains largely unproven, the distal colon has been regarded an ecologically suitable site for horizontal gene transfer (HGT) between microorganisms due to its high microbial cell density.2 We identified many gene families related to transposases and bacteriophages in the metagenomic data, but their over-representation was noted only in certain individuals (Supplementary Table S5). "

..." By analysing these contigs, we found that CTnRINT members contain a variety of genes, such as those for ABC-type multidrug transport systems, in the regions corresponding to that for the vancomycin-resistance genes on Tn1549 (data not shown). As shown in Fig. 6B, other known Tn1549-like CTns also contain various accessory genes in this region. These findings strongly suggest that the CTnRINT family is largely involved in the process of HGT in the human intestine. It seems reasonable that conjugal elements, which mediate genetic exchanges and transmittance through cell–cell contact, are key players in HGT in the colon."

***..."Thirdly, a survey of the enriched genes revealed an abundance of mobile genetic elements in the human intestinal gene pool, emphasizing that the human gut microbiota is a “hot spot” for HGT between microbes. Of particular importance is the abundance of conjugal elements including CTnRINT. Considering their high transfer efficiency, the broad range of hosts, and the frequent carriage of drug-resistance genes, ***it would be prudent to reassess the heavy use of antibiotics in modern medicine.

*** (or in GMOs for that matter, since they use an antibiotic resistance bacteria to mark almost all GMOs...And they have found rampant evidence that these antibiotic resistant microbes have taken over our soil and water ways...besides our bodies...Kim)

This study looked at breast feed children vs. adults...
..."We suggest that the infant-type can be viewed as unstable, yet dynamic and adaptable. Conversely, the functional uniformity observed in the adult-type microbiota (Figs. 1, 3B, and 4) may be attributable to its more complex nature (Fig. 2 and Tables 1 and S2), which in turn suggests that the insurance hypothesis for the benefit of biodiversity may be relevant to the gut."

This takes to another study...To explain "Insurance Hypothesis"
Biodiversity and ecosystem productivity in a fluctuating environment: the insurance hypothesis.
Yachi S, Loreau M
Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4):1463-8.
[PubMed] [Ref list]
Although the effect of biodiversity on ecosystem functioning has become a major focus in ecology, its significance in a fluctuating environment is still poorly understood. According to the insurance hypothesis, biodiversity insures ecosystems against declines in their functioning because many species provide greater guarantees that some will maintain functioning even if others fail. Here we examine this hypothesis theoretically. We develop a general stochastic dynamic model to assess the effects of species richness on the expected temporal mean and variance of ecosystem processes such as productivity, based on individual species' productivity responses to environmental fluctuations. Our model shows two major insurance effects of species richness on ecosystem productivity: (i) a buffering effect, i.e., a reduction in the temporal variance of productivity, and (ii) a performance-enhancing effect, i.e., an increase in the temporal mean of productivity. The strength of these insurance effects is determined by three factors: (i) the way ecosystem productivity is determined by individual species responses to environmental fluctuations, (ii) the degree of asynchronicity of these responses, and (iii) the detailed form of these responses. In particular, the greater the variance of the species responses, the lower the species richness at which the temporal mean of the ecosystem process saturates and the ecosystem becomes redundant. These results provide a strong theoretical foundation for the insurance hypothesis, which proves to be a fundamental principle for understanding the long-term effects of biodiversity on ecosystem processes."

This picture from another study ... is important...Shows antibiotic resistance in our gut...Read the side levels along the diagonal line...See the matching color on either side of the line...just spend some time looking and comparing colors and levels and where...Human and non-human...Are stomachs are the highest level it can go...maybe even higher...The pic doesn't show how high our guts content of antibiotic resistant really is.

..."Horizontal gene transfer (HGT), the acquisition of genetic material from non-parental lineages, is known to be important in bacterial evolution1, 2. In particular, HGT provides rapid access to genetic innovations, allowing traits such as virulence3, antibiotic resistance4 and xenobiotic metabolism5 to spread through the human microbiome. Recent anecdotal studies providing snapshots of active gene flow on the human body have highlighted the need to determine the frequency of such recent transfers and the forces that govern these events4, 5. Here we report the discovery and characterization of a vast, human-associated network of gene exchange, large enough to directly compare the principal forces shaping HGT. We show that this network of 10,770 unique, recently transferred (more than 99% nucleotide identity) genes found in 2,235 full bacterial genomes, is shaped principally by ecology rather than geography or phylogeny, with most gene exchange occurring between isolates from ecologically similar, but geographically separated, environments. For example, we observe 25-fold more HGT between human-associated bacteria than among ecologically diverse non-human isolates (P = 3.0 × 10−270). We show that within the human microbiome this ecological architecture continues across multiple spatial scales, functional classes and ecological niches with transfer further enriched among bacteria that inhabit the same body site, have the same oxygen tolerance or have the same ability to cause disease. This structure offers a window into the molecular traits that define ecological niches, insight that we use to uncover sources of antibiotic resistance and identify genes associated with the pathology of meningitis and other diseases."

Tuesday, July 28, 2015

Pesticide Misuse and Idiots

Came home from a weekend away today and saw some idiot was spraying all the people's mailboxes and up and down the side of the road...One side is a river edge...that goes into the ocean 2 miles down...And federal judges have ordered life be brought back to the river...Someone is not getting it...
And my nextdoor neighbor has poison all over her yard and our property line...I think her worker was using up the "rest of the tank" with all the spraying in the public areas...Which is where people go to smoke and sit off the property...We cannot smoke here, but it's OK to spray poison where ever you want...
I told our county council how they have killed 2 shop owners with their spraying in town where people walk gassing, even me in my face at 8am...Both died 9 days later...Heart problems...Pesticides make your blood clot and stick together...

Pesticide use needs to be outlawed completely...
When I get the Ag pesticide misuse they come and cover up for who or whatever...Pretending...even calling and warning the office of the HUD housing where I live...That has turned out to be the Pesticide Mixing House Area for the Wailuku Sugar Mill. Nothing was done...I'm just starting to walk right after 7 years...
Our only protections is ground cover...Last month 10 minutes prisoners from the jail were brought through and took away every bush...
We have chickens who scratch everywhere...Under my louvered bedroom windows...I have had a sore throat, runny nose cough and even a fever...I realized I did not have a cold after a month and closed off the bedroom and detoxed...House and myself...It is very gross...I covered all the dirt and construction TOMPs (Toxic Organic Micro Pollutants.) with a sheet to keep out the chickens...I might have to make another report to the main office...But, these people know nothing except lawsuits!

D of Health has found 2-4xs the "SAFE" amount of Arsenic and Dioxin in the soil here...
"Dioxin is a known human carcinogen and the most potent synthetic carcinogen ever tested in laboratory animals. A characterization by the National Institute of Standards and Technology of cancer causing potential evaluated dioxin as over 10,000 times more potent than the next highest chemical (diethanol amine), half a million times more than arsenic and a million or more times greater than all others.
The World Health Organization said
“Once dioxins have entered the environment or body, they are there to stay due to their uncanny ability to dissolve in fats and to their rock-solid chemical stability.”
That is because dioxins are classed as one of the persistant organic pollutants, POPs, also known as as PBTs (Persistent, Bioaccumulative and Toxic) or TOMPs (Toxic Organic Micro Pollutants.)
POPs are a small set of toxic chemicals that remain intact in the environment for long periods and accumulate in the fatty tissues of animals. They are extremely toxic and cause all manner of illnesses. You can find out more about POPS here"

And this family's story :
Most of our friends and family already know what our family is going through at the moment, but I am setting this post to 'public' so that it can be shared in Eugene, Portland or surrounding areas. (Or beyond)
Please, please, please feel free to share this post. Fellow Eugene residents have a right to know how our local businesses conduct themselves on an environmental basis. These issues affect all of us.

First of all I want to say, people have a right to grow pesticide free food on their own property. They have a right to let their pets and children play in their own backyard without having to fear they're being exposed to concentrated toxins. We pay our rent every month for the right to call this piece of property home. We've spent a year and a half transforming our backyard into a sustainable space where we can grow our own food, dry our laundry without use of electricity, raise our own chickens and tend honey bees. I cannot begin to calculate the amount of work we've invested here.

My family and I are Eugene residents. On Tuesday morning, July 21st, an employee at the business behind our house, Dust Busters Plus LLC, sprayed herbicide (Round Up mixed with Crossbow) along our shared fence line, inadvertently damaging almost all of the vegetation in our backyard, including our large, organic garden. We have spoken with the business owner personally, as well as hand delivered a letter detailing what happened along with an itemized bill for damages. He is not currently taking responsibility for the damages and has not offered any compensation to us at this time. In fact, he completely denies knowledge of having any herbicides on his property or telling his employee to do the spraying, even though I witnessed the employee spraying and spoke with him directly.
The employee stated to me "I'm just doing what my boss told me to." and didn't even know which chemicals he had mixed.
When we asked the owner about compensating us for the damages to our property he stated that he would "possibly consider compensation if we didn't involve the Department of Agriculture." He didn't even bother coming to look at what he had caused.

I contacted the Oregon State Department of Agriculture and a pesticide investigator came out to our house Thursday morning and took photos and samples of the vegetation in our yard which will be sent to their labs in Portland for examination. They are opening a case against the business.

At this point, due to the short time frame in which the damage to vegetation became visible, we believe that the employee that did the spraying did not dilute the concentrated herbicide before applying it. We've lost over $1000 dollars worth of plants already, not to mention all of the contaminated soil that will have to be removed from our raised beds, hauled away and disposed of.
As soon as the state report has been finalized we will be obtaining a copy and opening a civil suit against the business for damages to our property.
As I've researched these herbicides and the laws surrounding them, I've discovered that there really aren't many penalties for businesses who abuse pesticides in this manner. Chemicals like Round Up and Crossbow do not require any sort of licence to be used on personal property. In our case, it was a very young man who was told by his employer to mix the chemicals and apply them, without any supervision whatsoever. The weather conditions that morning were warm and windy, causing a large drift of herbicides to engulf our property, as well as possible volatilzation. The victims of negligence like this; families like ours who have lost thousands of dollars of investment, have very little recourse.
We have lost a year and a half's worth of work and all of our garden harvest for this year. It will take weeks to remove all of the dying vegetation and contaminated soil. It will be months before we know if this has affected our honey bee colony. As well as months before we see any resolution. It has been a heart breaking week to say the least. We still haven't fully decided if we will attempt to grow another garden in our backyard next year, fearful that this situation with repeat itself due to the negligence of this company's business practices.
We moved to Eugene because for the most part, I believe that it is an ecologically conscious community. As far as I am concerned, Eugene has no place for businesses like this one, who have a blatant disregard for our environment, wildlife or other people's property. They have created a toxic environment in our backyard, where our pets and children play. The business owner's answer for me was to simply fire the employee, as if the young man should be punished for doing what his employer instructed. I am honestly just appalled at the way he conducts himself and his business.
Lastly I just want to say, this can happen to anyone. Your fence WILL NOT protect you. If you find yourself in this situation, don't let them get away with it. Fight!
Call your State Agricultural department and report it. We all deserve the right to have healthy, uncontaminated space. Our children deserve a safe place to play and grow. No business or person should be able to take those things away from us. Let your voice be heard!

You Sparkle and You Know So...

What is DNA? Video at a microscopic level shows how the DNA is organized.
Your body is a community of 100 trillion cells, 10 trillion of them are human. Each of the 10 trillion cells has 1.8 meters on DNA. The molecular surface of a stem cell a molecular antenna, listening for messages.

U. of HI Faculty Distances itself from Monsanto...Wham BAM!

UHM faculty condemn academic freedom violations

The university's College of Tropical Agriculture and Human Resources has restricted and violated one of it's own professor's academic freedom, and a group of his professional colleagues are speaking out against his mistreatment. Sixty faculty members at the University of Hawaii at Manoa have signed a letter sent to Manoa Chancellor
Robert Bley-Vroman, the vice-chancellor for academic affairs, and Maria Gallo, Dean of the university’s College of Tropical Agriculture and Human Resources (CTAHR) asking that the university acknowledge the restrictions and violations of academic freedom imposed on CTAHR Professor Hector Valenzuela.

For years now, the college has been accepting money from agrochemical companies such as Monsanto while simultaneously advocating for a style of agriculture that is dependent on the products created by these companies, namely Genetically Modified Organisms that can withstand the use of the companies’ lucrative pesticides. Dr. Valenzuela’s field of expertise involves discovering ways in which crops can thrive in our climate without the use of the GMO-pesticide model of agriculture. The 20+ year CTAHR veteran spent six years in the early ‘90s developing the first long-term organic farming research project in Hawaii and the Pacific region. But around 1998, when Monsanto money began entering the equation, his research plot was shut down by the college. Over the next 15 years, Valenzuela tolerated what he calls a climate of “bigotry, retaliation and hostility” in retaliation for his failure to tow the dominant CTAHR line (documented in Paul Koberstein’s article “The Silencing of Hector Valenzuela,” published here). The university denies his accusations.

...2) “The role of CTAHR as a land-grant institution is to assist all members and sectors of Hawai‘i’s food and agricultural system to reach their full potential in an environmentally and socially compatible way.”

Increasingly, large areas of agricultural land, representing over 70% of the area devoted to the production of diversified and edible crops in Hawai’i, have been acquired through lease or purchase by five large seed-and-pesticide corporations (Monsanto, Syngenta, Dow Chemical, BASF and DuPont-Pioneer) that have come to Hawai‘i over the last five decades. Their purpose was not to improve or increase Hawai‘i’s food production but rather to exploit Hawai‘i’s ideal soil and climate conditions in order to grow and test genetically-engineered and pesticide-resistant seeds for export to other areas worldwide. It is surely questionable whether, in terms of a land-grant institution’s mission, such corporations should even be treated as members of “Hawai‘i’s food and agricultural system” at all. Yet CTAHR does not merely regard them as an indispensable part of “diversified agriculture”, it gives the appearance of favoring them over other branches, and has provided its full support, in articles, workshops, and outreach programs, to the various activities of these corporations. Time and energy used in such ways have inevitably detracted from time and energy that could have been spent in support of Hawai‘i’s food producers.

Pesticides...and Fibromyalgia...and other types of Cell Damage Cause...“trade secrets” Explained.. My Take!

"Samsel discusses one particular study on rabbits that looked at the effects of glyphosate on the skin. They monitored the rabbits’ blood chemistry, and one of their findings found an increase oflactate dehydrogenase, *an enzyme in the blood related to tissue damage.

(*Lactate dehydrogenase: (LDH) An enzyme that catalyzes the conversion of lactate to pyruvate. This is an important step in energy production in cells. two major types of lactate dehydrogenase: the M form and the H form ..These are very similar in size and shape, but they have different catalytic properties. The M form, which is the major form in your large skeletal muscles, is best at converting pyruvate to lactate. It stands ready to get to work if the muscles need to perform anaerobic exercise. The H form, on the other hand, is better at the opposite reaction, converting lactate to pyruvate. It is the major form in the heart, which has a constant supply of oxygen and can easily use lactate as an aerobic source of energy. The two types are so similar in structure that they form complexes with a mixture of both types, for instance, with two H chains and two M chains. In this way, different cells can tailor their lactate dehydrogenases to fit their current needs. )"

Shows the cause of Fibromyalgia...Where you cannot move with out terrible pain in the nerves that are in the muscles...Then imagine that is in every part of your body...but those parts do not move as much so you can't really tell except for the swelling in the joints and pain there too...and that is called arthritis...also pesticide poisoning...sometimes diagnosed as Rheumatoid arthritis...which is a Lupus symptom...which is also a pesticide poisoning that is misdiagnosed...

Plus the swelling in the joints is part of all the dead cell and tissue overload the body cannot handle for removal...Way too much...They treat that with steroid, Prednisone...But, barely helps...

There is no cure for pesticide poisoning...and it is never diagnosed as the cause of illnesses...even if you tell your doc that is the cause...There is nothing they can do why go there and get in trouble for falling out of the system.

SO...if the energy production is being harmed...Pesticides are ravaging the processes and the structures...of our Mitochondria and Fascia...

Images of Living Fascia: Muscle Attitudes

Dr. J.C. Guimberteau, creator of “Strolling Under the Skin” comes this new video in collaboration with J.P. Delange. In it, they demonstrate that muscle is a contractile structure completely included in the meshwork of the multifibrillar system described in “Strolling”
Tom says: For those who loved the unique images of living fascia under the skin and in the skin will be glad to know that Dr Guimberteau has turned his camera on the myofascia with stunning results. Great for teachers or for showing clients, this new film is just right up the bodyworker’s alley.”
 Clips from the new DVD by Dr JC Guimberteau Muscle Attitudes.

"As part of glycolysis, hydrogen from glucose is placed on NAD+ to form NADH. Normally, these hydrogen atoms are then transferred to oxygen to form water. If oxygen isn't available, the NADH builds up and there isn't enough NAD+ to continue using glycolysis to make ATP. That's where lactate dehydrogenase steps in: it combines pyruvate and NADH, producing lactic acid and NAD+. The NAD+ can then be recycled to do another round of glycolysis, quickly producing more energy for the sprint. However, lactic acid builds up and in a matter of a minute or so, you have to stop and let your body recover. As you catch your breath, your body converts the lactic acid back to pyruvate, where it enters your normal flow of aerobic energy production...
Lactate dehydrogenase is a safety valve in our pipeline of energy production. Most of the time, our cells break down glucose completely, releasing the carbon atoms as carbon dioxide and the hydrogen atoms as water. This requires a lot of oxygen. If the flow of oxygen is not sufficient, however, the pipeline of energy production gets stopped up at the end of glycolysis. Lactate dehydrogenase is the way that cells solve this problem, at least temporarily."

"Albert L. Lehninger, in Principles Of Biochemistry, teaches that while muscle cells can oxidize fats for prolonged energy demand and sugar (glucose) for immediate energy...the brain cell has only one CURRENCY FOR ENERGY, and that is glucose. Thus, under stress, exaggerated mental activity requires additional glucose for the brain cell to function. Not only must the brain cell have extra glucose to cope with stress, the cytoplasm and mitochondria of brain cells (neurons), must have all of the members of the B-complex in their biologically-active-form the coenzymes required for anaerobic and aerobic glycolysis. Minerals and trace elements must also be available optimally. Phosphorus, Potassium, Magnesium, Manganese and Calcium play important roles in the conversion of sugar into energy, within all cells of the body. Being deficient in the B-complex factors, one cannot properly convert sugar or glucose to pyruvic acid for the anaerobic glycolytic pathway of sugar metabolism in the cell cytoplasm. Without B1, pyruvic acid cannot be converted to coenzyme A and enter the mitochondria to participate in the citric acid cycle and form ATP. As a result, pyruvic acid accumulates in nervous tissue and piles up on nerve endings causing irritation. Then the cells signal for help.

The adrenal medula comes to the rescue, increases its function and hormone output...and, as a result, provides the mechanism and the stimulus for producing muscle and brain energy by gluconeogenesis. As long as adrenal hormone output is sufficient, one can survive all the symptoms of B-complex deficiency. The adrenal glands need protein, minerals and vitamin C (not ascorbic acid), especially tyrosinase (organic copper), to produce catecholamines. Without that extra energy, the person will flee, or cry, or hide. Emotionally they usually hide or separate from reality...the classical nervous breakdown, or nervous exhaustion. When this inevitable point is near at hand, the person not only needs total nutritional support, but also adrenal support. Besides those nutrients mentioned in the glycolytic phase, the Krebs energy cycle uses B3 five times, B1 two times, Pantothenic acid two times and Biotin three times. Biotin, normally synthesized in the intestines, is needed to transport CO2 from the cells into the circulation. Heavy metal toxicity blocks Biotin function, while antibiotics and chlorine in water, stop or restrict Biotin production in the intestinal tract. In the anaerobic phase of glycolysis, Fluoride blocks the very important enolase reaction, which impairs glucose metabolism. B2, Riboflavin or "G" combines with several enzymes and enzyme systems forming many flavo-proteins. It is present in retinal pigment contributing to visual acuity. "
Scientists from Singapore’s Nanyang Technological University (NTU Singapore) and McLean Hospital and Harvard Medical School in the United States have found that...
"Assoc Prof Yoon said the team had screened about 1000 FDA-approved drugs before they found two anti-malaria drugs which worked: chloroquine and aAmodiaquine. -

Exploring the Structure
The protozoan parasites that cause malaria are thought to rely on glycolysis for most of their energy during part of their cycle of infection. Researchers are now looking for drugs to block the action of lactate dehydrogenase as a way of attacking these parasites and curing the infection. The structure shown here (PDB entry 1cet) has four molecules of chloroquine bound in the active sites of the lactate dehydrogenase found in the Plasmodium parasite.

>>>Chloroquine is one of the major drugs used to treat malaria, however, its major site of action probably isn't at this enzyme; instead, it is thought to block the unusual methods that the parasite must use to feed on blood.

But researchers are exploring many other anti-malarial molecules that target lactate dehydrogenase, as seen in other PDB entries such as 1t24, 1t25, and similar structures.
Down in the atomic structure...
Adenosine diphosphate (ATP) in Mitochondria.
ATP, is an important organic compound in metabolism and is essential to the flow of energy in living cells.

ATP is creating the matrix of the Mitochondria.
Creating energy to spin and make more energy.
Making energy for protons and electrons...

A cycle supplying fuel with the spent products being brought back to be re-synthesized.
"A beautiful Machine"
We make ADP 50 -60 kilograms/110 - 132 pounds per day equivalent to our body weight.
95% of the oxygen we breath in is converted to WATER!

"A Beautiful Thing..."
Carries water throughout our bodies...
OHM Living Fascia 25x Magnified

The last 5 minutes of ATP Synthase: the Understood, the Uncertain, and the Unknown
Powering the Cell: Mitochondria
Phospholipids and Cardiolipids .. he says, are the secret to the structure mechanism of the machine that is the TREE OF LIFE.
I have an illness call Antiphospholipid Syndrome with AntiCardiolipin caused by pesticide poisoning...
This video opens a door to a better understanding.

A French study has linked glyphosate in Roundup to damage to human cells. The study showed cell death in placental cells, kidney cells, embryonic cells, and neonate umbilical cells. The study showed total cell death within 24 hours of being exposed to glyphosate, the active ingredient in Roundup. Cell death was reported at concentrations as low as .005 percent Roundup. Common causes of cell death was membrane rupture, mitochondrial damage, and cell asphyxia, or inability to respire. Cell damage was noted at concentrations 500 to 1,000 times lower than present accepted levels in agriculture.
February 21, 2013
In a new research paper published in the high ranked scientific journal Toxicology, Robin Mesnage, Benoît Bernay and Professor Gilles-Eric Séralini

"A groundbreaking new study finds synthetic (GMO) insulin is capable of rapidly producing type 1 diabetes in type 2 diabetics."
Here are some clues deep within our DNA/RNA/ATP/ADP that show why this happens...

The repressor protein is produced by a regulator gene. The region of DNA where the repressor protein binds is the operator site. The promoter site is a region of DNA where RNA polymerase can bind. The entire unit (promoter, operator, and genes) is an operon.
The operator acts like a switch that can turn several genes on or off at the same time.
The lac operon is an inducible operon that uses negative control. It is inducible because the structural genes are normally inactive but the presence of lactose induces them to become active. It is negative control because an active repressor prevents transcription.
ATP (Adenosine Triphosphate)
The energy in one glucose molecule is used to produce 36 ATP. ATP has approximately the right amount of energy for most cellular reactions.
ATP is produced and used continuously. The entire amount of ATP in an organism is recycled once per minute. Most cells maintain only a few seconds supply of ATP.
Transcription of the structural genes of the lac operon also requires reduced levels of glucose. The role of glucose in promoting transcription is discussed later (see Positive and Negative Control of the Lac Operon below).

Positive and Negative Control of the Lac Operon
The lac operon discussed earlier as an example of negative control is also an example of positive control. The cell normally uses glucose as a carbon source. When the level of glucose declines, the level of a signaling molecule called cyclic AMP (cAMP) increases. Cyclic AMP binds to a protein called CAP (catabolic activator protein) which then binds to the promoter region, causing transcription to occur. Reduced glucose, therefore, promotes the transcription of the lac Z, Y, and A genes. However, because the lac operon is inducible, lactose must be present.
By having both positive and negative control operating at the same time, the structural genes in the lac operon are not active unless the level of glucose is reduced and lactose is available.

Protein Activation
Some proteins are not active when they are first formed. They must undergo modification such as folding, enzymatic cleavage, or bond formation.
Example: Proinsulin is a precursor to the hormone insulin. It must be cleaved into 2 polypeptide chains and then some amino acids must be removed to form insulin.
Many proteins are activated by adding phosphate groups. They can be inactivated by removing phosphate groups. For example, kinases activate by adding phosphate groups and phosphodiesterase inactivates by removing the phosphate groups.
Feedback Control

Some enzymes in a metabolic pathway may be negatively inhibited by products of the pathway.
In oxidation-reduction reactions, coenzymes often remove electrons from the substrate and pass them to other molecules. Often the electron is added to a proton to form a hydrogen atom before it is passed. In this way, coenzymes serve to carry energy in the form of electrons (or hydrogen atoms) from one compound to another.

Vitamins are small organic molecules required in trace amounts. They usually act as coenzymes or precursors to coenzymes.

RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecules
. . . The pathway is also used as a practical tool in biotechnology, medicine and insecticides.[1]
. . . It is becoming increasingly clear that RNA binding proteins regulate posttranscriptional gene expression and play a critical role in RNA stability and translation.
. . . micronucleus test was performed to detect chromosomal damage...from spleen of rats... rats fed GM soyabean alone revealed a significant decrease in the amount of DNA...
. . . the activator binds to DNA and enables the binding of RNA polymerase.
. . . The mechanism for the decrease in the amount of DNA was discussed by Zhou et al. [27] who reported on hepatocellular degeneration, necrosis, DNA damage and the lesions of the extracellular matrix...could cause liver toxicity due to DNA strand breaks in hepatocytes.
. . . The binding of an inhibitor...alters the shape of the enzyme, resulting in a distorted active site that does not function properly.
. . . Poisons are inhibitors that bind irreversibly.

Historically, it was known by other names, including co-suppression, post transcriptional gene silencing (PTGS), and quelling. Only after these apparently unrelated processes were fully understood did it become clear that they all described the RNAi phenomenon.

USDA: RNA-interference Pesticides Will Need Special Safety Testing

The Effect of Extra Virgin Olive Oil and Soybean on DNA, Cytogenicity and Some Antioxidant Enzymes in Rats feeding as a dietary component.
Feasibility, limitation and possible solutions of RNAi-based technology for insect pest control.

"Numerous studies indicate that target gene silencing by RNA interference (RNAi) could lead to insect death. This phenomenon has been considered as a potential strategy for insect pest control, and it is termed RNAi-mediated crop protection. However, there are many limitations using RNAi-based technology for pest control, with the effectiveness target gene selection and reliable double-strand RNA (dsRNA) delivery being two of the major challenges. With respect to target gene selection, at present, the use of homologous genes and genome-scale high-throughput screening are the main strategies adopted by researchers. Once the target gene is identified, dsRNA can be delivered by micro-injection or by feeding as a dietary component."

very specific ?
...for use in potential plant-based RNAi control strategies. Delivery of dsRNA expressed by genetically modified crops to the midgut of phytophagous insects is under investigation as a new tool for very specific protection of plants from insect pest species. The T. castaneum screening platform offers a system for discovery of candidate genes with high potential benefit.

Understanding how we make electricity in our body and use it for energy...
A phosphate molecule breaks off from the string of 3 and creates a spark...

Adenosine triphosphate (ATP) is a multifunctional nucleoside triphosphate used in cells as a coenzyme. ATP transports chemical energy within cells for metabolism. It's one of the end products of photophosphorylation and cellular respiration and used by enzymes and structural proteins in many cellular processes, including biosynthetic reactions and cell division. One molecule of ATP contains three phosphate groups, and it is produced by ATP synthase from inorganic phosphate and adenosine diphosphate (ADP).

Adenosine diphosphate, abbreviated ADP consists in two phosphate group, the pentose sugar ribose, and the nucleobase adenine. ADP is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. ADP is the end-product that results when ATP loses one of its phosphate groups. The conversion of these two molecules plays an important role in supplying energy for many processes of life. One molecule of ATPproduces 7.3 kcal.

Powering the Cell: Mitochondria

Animals use the energy released in the breakdown of glucose and other molecules to convert ADP to ATP, which can then be used to fuel necessary growth and cell maintenance.

Roundup (Glyphosate) May Be The Most Biologically Disruptive Chemical in Our Environment – Monsanto has known about research connecting glyphosate to cancer since the 1970s.

by Samsmall on July 18, 2015 in Maui Causes Blog

Fibromyalgia is described here...
It develops when the immune system mistakes the myelin that surrounds the nerve fibres in the brain and spinal cord for a foreign body.
It strips the myelin off the nerves fibres, which disrupts messages passed between the brain and body causing problems with speech, vision and balance.
Another of the study's authors, Professor David Hafler, from Yale University, said that nature had clearly not intended for the immune system to attack its host body, so he expected that an external factor was playing a part.
He said: 'These are not diseases of bad genes alone or diseases caused by the environment, but diseases of a bad interaction between genes and the environment.