Wednesday, July 9, 2014

Strike 3 DNA/RNA GMO Science False

A revolutionary new study reveals that the core tenet of classical genetics is patently false, and by implication: what we do in this life -- our diet, our mindset, our chemical exposures -- can directly impact the DNA and health of future generations.

A paradigm shifting new study titled, "Soma-to-Germline Transmission of RNA in Mice Xenografted with Human Tumour Cells: Possible Transport by Exosomes," promises to overturn 
several core tenets of classical genetics
including collapsing the timescale necessary for the transfer of genetic information
through the germline of a species (e.g. sperm) 
from hundreds of thousands of years to what amounts to 'real time' changes in biological systems.

...In classical genetics, Mendelian laws specify that the inheritance of traits passed from one generation to the next can only occur through sexual reproduction as information is passed down through the chromosomes of a species' germline cells (egg and sperm), and never through somatic (bodily) cells.  Genetic change, according to this deeply entrenched view, can take hundreds, thousands and even millions of generations to manifest.
The new study, however, has uncovered a novel mechanism through which somatic-to-germline transmission of genetic information is made possible.  Mice grafted with human melanoma tumor cells genetically manipulated to express genes for a fluorescent tracer enzyme (EGFP-encoding plasmid) were found to release information-containing molecules containing the EGFP tracer into the animals' blood; since EGFP is a non-human and non-murine expressed tracer, there was little doubt that the observed phenomenon was real.
...The implications of research on exosome-mediated information transfer are wide ranging. First, if your somatic cells, which are continually affected by your nutritional, environmental, lifestyle and even mind-body processes, can transfer genetic information through exosomes to the DNA within your germline cells, then your moment-to-moment decisions, behaviors, experiences, toxin and toxicant exposures, could theoretically affect the biological 'destinies' of your offspring, and their offspring, stretching on into the distant future. 
Exosome research also opens up promising possibilities in the realm of nutrigenomics and 'food as medicine.' A recent study found common plant foods, e.g. ginger, grapefruit, grapes, produce exosomes that, following digestion, enter human blood undegraded and subsequently down-regulate inflammatory pathways in the human body in a manner confirming some of their traditional folkloric medicinal uses.  If the somatic cells within our body are capable through extrachromosomal processes of modulating fundamental genetic processes within the germline cells, or, furthermore, if foods that we eat are also capable of acting as vectors of gene-regulatory information, truly the old reductionist, mechanistic, unilinear models of genetics must be abandoned in favor of a view that accounts for the vital importance of all our decisions, nutritional factors, environmental exposures, etc., in determining the course, not only of our bodily health, but the health of countless future generations as well.
http://www.greenmedinfo.com/blog/no-sex-required-body-cells-transfer-genetic-info-directly-sperm-cells-amazing

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