RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecules
. . . The pathway is also used as a practical tool in biotechnology, medicine and insecticides.[1]
. . . It is becoming increasingly clear that RNA binding proteins regulate posttranscriptional gene expression and play a critical role in RNA stability and translation.
. . . micronucleus test was performed to detect chromosomal damage...from spleen of rats... rats fed GM soyabean alone revealed a significant decrease in the amount of DNA...
. . . the activator binds to DNA and enables the binding of RNA polymerase.
. . . The mechanism for the decrease in the amount of DNA was discussed by Zhou et al. [27] who reported on hepatocellular degeneration, necrosis, DNA damage and the lesions of the extracellular matrix...could cause liver toxicity due to DNA strand breaks in hepatocytes.
. . . The binding of an inhibitor...alters the shape of the enzyme, resulting in a distorted active site that does not function properly.
. . . Poisons are inhibitors that bind irreversibly.
Historically, it was known by other names, including co-suppression, post transcriptional gene silencing (PTGS), and quelling. Only after these apparently unrelated processes were fully understood did it become clear that they all described the RNAi phenomenon.
USDA: RNA-interference Pesticides Will Need Special Safety Testing
http://www.gmoevidence.com/usda-rna-interference-pesticides-will-need-special-safety-testing/
The Effect of Extra Virgin Olive Oil and Soybean on DNA, Cytogenicity and Some Antioxidant Enzymes in Rats
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073157/
![Photo: RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecules
. . . The pathway is also used as a practical tool in biotechnology, medicine and insecticides.[1]
. . . It is becoming increasingly clear that RNA binding proteins regulate posttranscriptional gene expression and play a critical role in RNA stability and translation.
. . . micronucleus test was performed to detect chromosomal damage...from spleen of rats... rats fed GM soyabean alone revealed a significant decrease in the amount of DNA...
. . . the activator binds to DNA and enables the binding of RNA polymerase.
. . . The mechanism for the decrease in the amount of DNA was discussed by Zhou et al. [27] who reported on hepatocellular degeneration, necrosis, DNA damage and the lesions of the extracellular matrix...could cause liver toxicity due to DNA strand breaks in hepatocytes.
. . . The binding of an inhibitor...alters the shape of the enzyme, resulting in a distorted active site that does not function properly.
. . . Poisons are inhibitors that bind irreversibly.
Historically, it was known by other names, including co-suppression, post transcriptional gene silencing (PTGS), and quelling. Only after these apparently unrelated processes were fully understood did it become clear that they all described the RNAi phenomenon.
#MONSANTO #RNAi
USDA: RNA-interference Pesticides Will Need Special Safety Testing
http://www.gmoevidence.com/usda-rna-interference-pesticides-will-need-special-safety-testing/
The Effect of Extra Virgin Olive Oil and Soybean on DNA, Cytogenicity and Some Antioxidant Enzymes in Rats
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073157/](https://fbcdn-sphotos-f-a.akamaihd.net/hphotos-ak-xpa1/t1.0-9/10406826_885116914849264_3799290160669646661_n.jpg)
The elephant is in the room.
We will all be squished...
...by feeding as a dietary component.
Feasibility, limitation and possible solutions of RNAi-based technology for insect pest control.
"Numerous studies indicate that target gene silencing by RNA interference (RNAi) could lead to insect death. This phenomenon has been considered as a potential strategy for insect pest control, and it is termed RNAi-mediated crop protection. However, there are many limitations using RNAi-based technology for pest control, with the effectiveness target gene selection and reliable double-strand RNA (dsRNA) delivery being two of the major challenges. With respect to target gene selection, at present, the use of homologous genes and genome-scale high-throughput screening are the main strategies adopted by researchers. Once the target gene is identified, dsRNA can be delivered by micro-injection or by feeding as a dietary component."
. . . The pathway is also used as a practical tool in biotechnology, medicine and insecticides.[1]
. . . It is becoming increasingly clear that RNA binding proteins regulate posttranscriptional gene expression and play a critical role in RNA stability and translation.
. . . micronucleus test was performed to detect chromosomal damage...from spleen of rats... rats fed GM soyabean alone revealed a significant decrease in the amount of DNA...
. . . the activator binds to DNA and enables the binding of RNA polymerase.
. . . The mechanism for the decrease in the amount of DNA was discussed by Zhou et al. [27] who reported on hepatocellular degeneration, necrosis, DNA damage and the lesions of the extracellular matrix...could cause liver toxicity due to DNA strand breaks in hepatocytes.
. . . The binding of an inhibitor...alters the shape of the enzyme, resulting in a distorted active site that does not function properly.
. . . Poisons are inhibitors that bind irreversibly.
Historically, it was known by other names, including co-suppression, post transcriptional gene silencing (PTGS), and quelling. Only after these apparently unrelated processes were fully understood did it become clear that they all described the RNAi phenomenon.
USDA: RNA-interference Pesticides Will Need Special Safety Testing
http://www.gmoevidence.com/usda-rna-interference-pesticides-will-need-special-safety-testing/
The Effect of Extra Virgin Olive Oil and Soybean on DNA, Cytogenicity and Some Antioxidant Enzymes in Rats
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073157/
The elephant is in the room.
We will all be squished...
Feasibility, limitation and possible solutions of RNAi-based technology for insect pest control.
"Numerous studies indicate that target gene silencing by RNA interference (RNAi) could lead to insect death. This phenomenon has been considered as a potential strategy for insect pest control, and it is termed RNAi-mediated crop protection. However, there are many limitations using RNAi-based technology for pest control, with the effectiveness target gene selection and reliable double-strand RNA (dsRNA) delivery being two of the major challenges. With respect to target gene selection, at present, the use of homologous genes and genome-scale high-throughput screening are the main strategies adopted by researchers. Once the target gene is identified, dsRNA can be delivered by micro-injection or by feeding as a dietary component."
http://www.pubfacts.com/detail/23955822/Feasibility-limitation-and-possible-solutions-of-RNAi-based-technology-for-insect-pest-control.
very specific ?
...for use in potential plant-based RNAi control strategies. Delivery of dsRNA expressed by genetically modified crops to the midgut of phytophagous insects is under investigation as a new tool for very specific protection of plants from insect pest species. The T. castaneum screening platform offers a system for discovery of candidate genes with high potential benefit.
very specific ?
...for use in potential plant-based RNAi control strategies. Delivery of dsRNA expressed by genetically modified crops to the midgut of phytophagous insects is under investigation as a new tool for very specific protection of plants from insect pest species. The T. castaneum screening platform offers a system for discovery of candidate genes with high potential benefit.
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