**"This dilution level is far below agricultural recommendations and corresponds to low levels of residues in food or feed. "**
++"through an inhibition of the mitochondrial succinate dehydrogenase activity, and necrosis, by release of cytosolic adenylate kinase measuring membrane damage. They also induce apoptosis via activation of enzymatic caspases 3/7 activity. This is confirmed by characteristic DNA fragmentation, nuclear shrinkage (pyknosis), and nuclear fragmentation (karyorrhexis), which is demonstrated by DAPI in apoptotic round cells. G provokes only apoptosis, and HUVEC are 100 times more sensitive overall at this level. The deleterious effects..." ++
http://www.pesticidescancer.eu/spip.php?article23
Organophosphate poisoning leads to the irreversible blockade of antocholinesterase which results in a cholingeric crisis.
If diagnosed soon after exposure, orgnaophosphate poisoning may be reversed by administering pralidoxime (2-PAM) which breaks the covalent bond between the phosphate of the pesticide and the esteratic group of acetylcholinesterase. Delayed toxicity is associated with peripheral neuropathy ( ataxia and motor weakness) due to axonal degeneration.
"Previous studies have revealed that at low doses, organophosphorus pesticides not only act as genotoxic agents but also affect several other biochemical pathways. The aim of the current investigation was to assess apoptosis and necrosis caused by these pesticides on human peripheral blood lymphocytes under in vitro conditions using the DNA diffusion assay. Our studies have revealed that all the above pesticides induced apoptosis and necrosis in cultured human peripheral blood lymphocytes in in vitro conditions. The results are statistically significant (p < 0.001). Data on these alterations of immune cells are required for understanding the subchronic effects mediated by pesticides on nontarget organisms."
http://www.ncbi.nlm.nih.gov/pubmed/16707324
++"through an inhibition of the mitochondrial succinate dehydrogenase activity, and necrosis, by release of cytosolic adenylate kinase measuring membrane damage. They also induce apoptosis via activation of enzymatic caspases 3/7 activity. This is confirmed by characteristic DNA fragmentation, nuclear shrinkage (pyknosis), and nuclear fragmentation (karyorrhexis), which is demonstrated by DAPI in apoptotic round cells. G provokes only apoptosis, and HUVEC are 100 times more sensitive overall at this level. The deleterious effects..." ++
http://www.pesticidescancer.eu/spip.php?article23
Organophosphate poisoning leads to the irreversible blockade of antocholinesterase which results in a cholingeric crisis.
If diagnosed soon after exposure, orgnaophosphate poisoning may be reversed by administering pralidoxime (2-PAM) which breaks the covalent bond between the phosphate of the pesticide and the esteratic group of acetylcholinesterase. Delayed toxicity is associated with peripheral neuropathy ( ataxia and motor weakness) due to axonal degeneration.
"Previous studies have revealed that at low doses, organophosphorus pesticides not only act as genotoxic agents but also affect several other biochemical pathways. The aim of the current investigation was to assess apoptosis and necrosis caused by these pesticides on human peripheral blood lymphocytes under in vitro conditions using the DNA diffusion assay. Our studies have revealed that all the above pesticides induced apoptosis and necrosis in cultured human peripheral blood lymphocytes in in vitro conditions. The results are statistically significant (p < 0.001). Data on these alterations of immune cells are required for understanding the subchronic effects mediated by pesticides on nontarget organisms."
http://www.ncbi.nlm.nih.gov/pubmed/16707324
PA for review to re approve glyphosate. Glyphosate is a chemical sprayed on 80% of GMOs, which make up 90% of our food crops which end up in 85% of America's processed food. It does not wash or cook off. Our infertility/sterility/miscarriage rate is 30% in the USA, the highest in recorded history. This rate directly correlates with pigs which consumed glyphosate sprayed grains and jumped from 3% to 30% miscarriage rate, then back down to 3% when they ate non-glyphosate sprayed grains. These are our babies. We will protect them!
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